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Can TLC or paper chromatography be used to separate and identify very volatile substances? Explain.

Can TLC or paper chromatography be used to separate and identify very volatile substances? Explain.

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No, TLC or paper chromatography cannot be used to separate and identify very volatile substances. This is because developing solvent has to be evaporated off using heating process, hence volatile substance will be removed.

For separation and identification of very volatile substances HPLC or GC (high performance liquid or gas chromatography) can be used.

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