ATCase is an important enzyme in DNA replication. a) What does this enzyme do and what are its substrates? b) This enzyme demonstrates feedback regulation. Describe its quaternary structure in this regard. c) Besides substrate(s) and product, what other molecules are involved in the feedback regulation of ATCase? Describe their function and how they interact?
1 Aspartate transcarbomylase is involved in pyrimidine biosynthesis. It catalyzes the first step of the condensation reaction. Its substrates are aspartate and carbomyl phosphate and products are carbamyl aspartate.
b Its structure consists of 12 subunits. Two catalytic trimers and three regulatory dimers. Two catalytic trimers is holoenzyme which is held together by three regulatory dimers. Regulatory dimers involved in regulating activity.
C other than substrates and products, end product of this biosynthetic pathway involved in regulation. High CTP concentrations blocks the pathway by inhibiting the enzyme. Low levels of CTP increases the enzyme activity. This regulatory phenomena is regulated by binding and non-binding of CTP. High levels tend to binding and low levels tend to non-binding. Thereby regulates the pathway and this enzyme involved step is rate limiting step.
ATCase is an important enzyme in DNA replication. a) What does this enzyme do and what...
ATCase is an important enzyme in DNA replication. a) What does this enzyme do and what are its substrates? b) This enzyme demonstrates feedback regulation. Describe its quaternary structure in this regard. c) Besides substrate(s) and product, what other molecules are involved in the feedback regulation of ATCase? Describe their function and how they interact?
10. With regard to transcription, the enzyme begins of a DNA transcribing RNA after it attaches to the molecule. With regard to translation, the begins translating a polypeptide after it attaches to the __ of an mRNA molecule. Start and stop codons are involved in the process of The start codon is , while the stop codons are 11. and Does the start codon specify an amino acid? If so, which one(s)? Do the stop codons specify an amino acid?...
DNA Replication - Describe the process of DNA replication in a well-organized manner. Start with the helicase and go through the entire process, step by step. Use these terms correctly: Helicase, DNA primase, single stranded binding proteins, DNA polymerase I, DNA Polymerase III, leading strand, lagging strand, okazaki fragments, ligase, topoisomerase, sliding clamp, clamp loader. Please use correct descriptions of the enzyme function. For example, do not say, “seals nicks.” Tell me what “seals nicks” means.
Describe the structure of DNA List the steps involved in DNA Replication What is crossing over? (Honors Only) What occurs during nondisjunction? What is a monosomy, and a trisomy? Give examples of disorders caused by each.
Question 5 1 pts The enzyme helicase is an important part of the replication machinery, but its use now requires specifically the activity of the following enzyme: Topoisomerase ODNA polymerase Sliding clamp Primase Ligase Question 7 1 pts Much of replication can be studied using extracts from wild type (normal) yeast cells that supply all of the essential components. Compared to wild type extracts, if you use an extract that is missing the sliding clamp AND ligase, what do you...
What other DNA polymerases are involved in DNA replication and when are they active? Although Dpb3 and Dpb4 are considered non-essential, DNA polymerase ? dissociates more frequently from the template when Dpb3 and Dpb4 are deleted. What are the explanations for this result? What do you think would happen if, in addition to Dpb3 and Dpb4 deletion, the exonuclease activity of Pol2 was also mutated in such a way that it did not function? How might replication fork progression and...
5. What is the difference between the replication fork within bacterial and a huma 6. What are leading and lagging strands? 7. In which direction does replication occur? 8. What are Okazaki fragments? 9. List the names of 8 proteins involved in replication and also define their function 10. What is the Function of RNA Primase? 11. Which enzyme removes the RNA from the replicatied DNA? 12. What are the functions of enzyme DNA polymerase? 13. In which direction does...
DNA polymerases I, III, and delta have important roles in replication. Which of these proteins have similar functions? Describe those similar functions that they share. Which one performs a different function and what is that function?
1. Describe one experiment that can test the hypothesis that DNA replication is semi conservative. Describe the results of this experiment if replication was conservative. And if it was distributive? 2. What type of chemical bond contributes to the specificity of base paring in the DNA? Are there any other chemical or physical factors in the structure o f the DNA molecule contributing to the thermodynamic stability of the DNA? 3. List the m ajor differences between DNA and RNA....
What do DNA and RNA have in common? NA Structure and Replication apter 10 Reading Quiz Question 3 Part A What do DNA and RNA have in common? View Available Hint(s) O Both are composed of nucleotides. O Both contain deoxyribose. O Both form double helices. They are composed of the same nucleotides. Submit Provide Feedback