What do you think is the advantage of graded potential vs action potential?
Graded Potentials | Action Potentials |
1). Depending on the stimulus, graded potentials can be depolarizing or hyperpolarizing. | 1).Action potentials always lead to depolarization of membrane and reversal of the membrane potential. |
2).Amplitude is proportional to the strength of the stimulus. | 2).Amplitude is all-or-none; strength of the stimulus is coded in the frequency of all-or-none action potentials generated. |
3).Amplitude is generally small (a few mV to tens of mV). | 3).Large amplitude of ~100 mV. |
4).Duration of graded potentials may be a few milliseconds to seconds. | 4).Action potential duration is relatively short; 3-5 ms. |
5).Ion channels responsible for graded potentials may be ligand-gated (extracellular ligands such as neurotransmitters), mechanosensitive, or temperature sensitive channels, or may be channels that are gated by cytoplasmic signaling molecules. | 5).Voltage-gated Na+ and voltage-gated K+ channels are responsible for the neuronal action potential. |
6).The ions involved are usually Na+, K+, or Cl−. | 6).The ions involved are Na+ and K+ (for neuronal action potentials). |
7).No refractory period is associated with graded potentials. | 7).Absolute and relative refractory periods are important aspects of action potentials. |
8).Graded potentials can be summed over time (temporal summation) and across space (spatial summation). | 8).Summation is not possible with action potentials (due to the all-or-none nature, and the presence of refractory periods). |
9).Graded potentials travel by passive spread (electrotonic spread) to neighboring membrane regions. | 9).Action potential propagation to neighboring membrane regions is characterized by regeneration of a new action potential at every point along the way. |
10).Amplitude diminishes as graded potentials travel away from the initial site (decremental). | 10).Amplitude does not diminish as action potentials propagate along neuronal projections (non-decremental). |
11).Graded potentials are brought about by external stimuli (in sensory neurons) or by neurotransmitters released in synapses, where they cause graded potentials in the post-synaptic cell. | 11).Action potentials are triggered by membrane depolarization to threshold. Graded potentials are responsible for the initial membrane depolarization to threshold. |
12).In principle, graded potentials can occur in any region of the cell plasma membrane, however, in neurons, graded potentials occur in specialized regions of synaptic contact with other cells (post-synaptic plasma membrane in dendrites or soma), or membrane regions involved in receiving sensory stimuli. | 12).Occur in plasma membrane regions where voltage-gated Na+ and K+channels are highly concentrated. |
What do you think is the advantage of graded potential vs action potential?
What can causes the graded potential in this action potential graph? There are two presynaptic neurons and one postsynaptic neuron | Figurel time (ms)
Period. DLDE How d graded current is different from an action potential. Make sure you think about: evenirea D Percom • Where in a neuron these take place and the direction they travel. • How does the strength of the signals change as it travels • Explain any differences in the velocity (how fast) of travel 56. Describe the 3 classifications of axons based on size and velocity of propagation. 57. The release of a neurotransmitter is dependent on what...
Ldlicu upon 16 What is the difference between a graded potential and an action potential? Where would a praded potential occur in the neuron? An action potential? 16. The most widely used inhibitory neurotransmitter is This neurotransmitter opens up ion channels in the postsynaptic membrane. Ions rush (in/out) and bring the cell (closer to/further from) threshold level. 17. Label the following diagram with these terms: depolarization, repolarization, hyperpolarization, Na gates open, Na' gates closed, K gates open, K' gates closed,...
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