Question

QUESTION 1

1. Which of the following processes/pathways CANNOT occur in the absence of O₂?

   		Oxidative phosphorylation
   		Substrate level phosphorylation
   		Oxidation of NADH
   		Photosynthesis
   		Fermentation

1 points   

QUESTION 2

1. Phosphofructokinase (PFK-1) is one of the most regulated enzymes in metabolism. Which of the following would be expected to be an allosteric inhibitor of PFK-1?

   		Glucose
   		Fructose-6-phosphate
   		Acetyl CoA
   		AMP

1 points   

QUESTION 3

1. Which of the following is a reactant of the first reaction of glycolysis?

   		Glucose
   		ADP
   		ATP
   		O2
   		Both glucose and ATP

1 points   

QUESTION 4

1. A high-energy bond in _________ provides the energy for the first reaction of the Citric Acid Cycle.

   		Oxaloacetate (OAA)
   		Citric acid
   		ATP
   		Acetyl-CoA

1 points   

QUESTION 5

1. What is required for fermentation?

   		O2
   		ATP
   		NADH
   		Pyruvate
   		Both NADH and pyruvate

Answer 1

Question 1: Oxidative Phosphorylation (this is the final step of cellular respiration where O2 is absolutely required)

Question 2: Acetyl CoA (Acetyl CoA inhibits PFK1 with high affinity and reversibly. This is a mechanism by which the glycolytic flux is strongly integrated with lipid metabolism in the body)

Question 3: Both Glucose and ATP. (In the first reaction of Glycolysis Glucose is converted to glucose 6-phosphate while ATP gets converted into ADP.)

Question 4: Acetyl CoA (Hydrolysis of the thioester linkage in Acetyl CoA drives the first reaction of Krebs Cycle)

Question 5: Both NADH and Pyruvate (In fermentation Glucose is converted to pyruvate while NAD+ is converted to NADH. the pyruvate forms acetaldehyde which in turn produces ethanol. In the process of conversion of acetaldehyde to ethanol NADH is converted back to NAD+)