Question

Draw a diagram explaining what is meant by an Exon-skipping drug

Answer 1

As the name suggests, the principle of omitting an exon is to encourage the cellular mechanism to "jump on" an exon. Small pieces of DNA called antisense oligonucleotides (AOs) or "molecular patches" are used to mask the exon you want to skip, in such a way as to be ignored during protein production. In our example, if we use a "molecular or chalk patch" designed to mask the exon 53:

Please do give thumbs up .