What are the targets of the antibiotics. Pyrazinamide Vancomycin Chloramphenicol Ampicillin Streptomycin Ciprofloxacin (a Fluoroquinolone) The...
What are the targets of the antibiotics.
Pyrazinamide
Vancomycin
Chloramphenicol
Ampicillin
Streptomycin
Ciprofloxacin (a Fluoroquinolone)
The options are: bacterial cell wall synthesis, bacterial ribosome, bacterial DNA synthesis, or cytoplasmic membrane
Homework Answers
Answer= The targets of the antibiotics.
Vancomycin - Bacterial cell wall synthesis.
Explanation -Vancomycin is a glycopeptide with a high molecular weight.It binds to free carboxyl end of the pentapeptide,specially interfering with cross linking of the peptidoglycan backbone.
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Chloramphenicol = bacterial ribosome
Explanation - Choramphenicol bind to the large subunit of prokaryotic ribosomes and interferes with functioning of peptide synthetase,thereby inhibiting chain elongation.
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Ampicillin -bacterial cell wall synthesis
inhibits third step of bacterial cell wall synthesis.
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Streptomycin - Bacterial ribosome
Explanation = Streptomycin binds to the protein S12 of the small ribosome subunit ,causing release of N-formylmet-tRNA from initiation complexes.
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Ciprofloxacin (a Fluoroquinolone) -Bacterial DNA synthesis.
Explanation - inhibit the nucleic acid synthesis,these are the synthetic antibiotics inhibit DNA replication.
Add Answer to:
What are the targets of the antibiotics.
Pyrazinamide
Vancomycin
Chloramphenicol
Ampicillin
Streptomycin
Ciprofloxacin (a Fluoroquinolone)
The...
Gram +ve Resistant Strains (%) 100 BOS Ribosome 90 50 Ribosome 80 Folate Pathway 70 DNA/RNA...
Gram +ve Resistant Strains (%) 100 BOS Ribosome 90 50 Ribosome 80 Folate Pathway 70 DNA/RNA Synthesis 60 Cell Wall Synthesis Fell Membrane Synercid Antibiotic (20 kg/ml) Apramycin Gentamicin Neomycin Streptomycin Tetracycline Minocycline Tigecycline Clindamycin Chloramphenicol Gram -ve 100 305 Ribosome 90 505 Ribosome Folate Pathway 70 DNA/RNA Synthesis Cell Wall Synthesis Resistant Strains (%) Antibiotic (20 wg/ml) Erythromycin Telithromycin Linezolid Sulfamethoxazole Apramycin Trimethoprim Gentamicin Ciprofloxacin Neomycin Novobiocin Streptomycin Rifampicin Tetracycline Vancomycin Meropenem Minocycline Cefotaxime Tigecycline Cephalexin Clindamycin Fosfomycin Chloramphenicol...
Which antimicrobial drug has narrow spectrum of activity? Tetracyclines Chloramphenicol Streptomycin Vancomycin 12. Quinolones are synthetic...
Which antimicrobial drug has narrow spectrum of activity? Tetracyclines Chloramphenicol Streptomycin Vancomycin 12. Quinolones are synthetic antimicrobials that... Blocks folic acid synthesis Inhibit DNA replication Inhibit cell wall synthesis Affect the cell envelope
The fluoroquinolone family of antibiotics (the most famous of which is ciprofloxacin, better known as Cipro),...
The fluoroquinolone family of antibiotics (the most famous of which is ciprofloxacin, better known as Cipro), work by allowing bacterial topoisomerase to start working and cut one DNA strand, but prevents the next steps from working. It specifically targets the bacterial version of topoisomerase so it does not affect the host cell function, Draw a diagram showing the function of topoisomerase (DNA gyrase) Explain what would happen to the bacterial cells when treated with the drug (be specific). Choose which sentence...
SUMMARY OF ANTIBIOTICS USED FOR KIRBY-BAUER DISK DIFFUSION SENSITIVITY Antiblotic Name Natural, Semi Spectrum of Activity:...
SUMMARY OF ANTIBIOTICS USED FOR KIRBY-BAUER DISK DIFFUSION SENSITIVITY Antiblotic Name Natural, Semi Spectrum of Activity: Active Against GP, Mechanism of Action* Side Effects/Other or Synthetce? Broad or Narrow? GN or both Vancomycin Erythromycin Sulfamethoxasole Trimethoprim Cefazolin Ciprofloxacin Ampicillir Oxacillin Gentamicin Ceftazidime Linezolid Daptomycin Ceftobiprole Cell wall synthesis inhibitor, protein synthesis inhibitor, disruptor of cytoplasmic membrane, metabolic pathway inhibitor, DNA/RNA synthesis inhibitor
2) List the major targets of an antimicrobial drug. What do all of these targets have...
2) List the major targets of an antimicrobial drug. What do all of these targets have in common? 3) Why is the Kirby-Bauer test standardized? 4) What is the advantage of the broth dilution tests for antibiotic sensitivity over the Kirby Bauer? 5) In general, why are Gram negative bacteria resistant to some of the antibiotics that Gram positive bacteria are sensitive to? 6) Fill in the following chart. ANTIBIOTIC CELLULAR TARGET AMPICILLIN CHLORAMPHENICOL ERYTHROMYCIN GENTAMICIN PENICILLIN STREPTOMYCIN TETRACYCLIN VANCOMYCIN
How do streptomycin and simlar antiblotics affect prokaryotic cells? 。These antibiotics interfere with peptidoglycan formation. O...
How do streptomycin and simlar antiblotics affect prokaryotic cells? 。These antibiotics interfere with peptidoglycan formation. O These antiblotics interfere with protein synthesls. O These antiblotics Interfere with DNA replication. O These antiblotics Interfere with cell wall formation. These antibiotics interfere with cell membrane integrity. 2. Why are eukaryotic cells unaffected by streptomycin and similar antiblotics? 0 Eukaryotic cells have organelles called lysosomes that engulf and break down these types of antibiotics. O Eukaryotic protein synthesis is not disrupted because these...
2) List the major targets of an antimicrobial drug What do all of these ta common?...
2) List the major targets of an antimicrobial drug What do all of these ta common? all of these targets have in 3) Why is the Kirby-Bauer test standardized? 4) What is the advantage of the broth dilution tests for antibiotic sensitivity over Kirby Bauer? 5) In general, why are Gram negative bacteria resistant to some of the antibiotics that Gram positive bacteria are sensitive to? 6) Fill in the following chart. ANTIBIOTIC CELLULAR TARGET AMPICILLIN CHLORAMPHENICOL ERYTHROMYCIN GENTAMICIN PENICILLIN...
Which of the following antibiotics is a cell wall inhibitor but is not a beta-lactam? Vancomycin...
Which of the following antibiotics is a cell wall inhibitor but is not a beta-lactam? Vancomycin а b Penicillin Cephalosporin d Monobactams Carbapenems е au Joshua, a cancer patient, is placed on the chemotherapeutic docetaxel and an additional drug that causes immunosuppression to decrease the possibility of hypersensitivity to the chemotherapeutic. Which of the following would this drug be? Corticosteroid a b Mineralcorticoid Gonadocorticoid C Antibiotics that work as protein synthesis inhibitors generally disrupt translation by working at the Enzyme...
Label the image to review major targets of drugs acting on bacterial cells. Cephalosporins Protein synthesis...
Label the image to review major targets of drugs acting on bacterial cells. Cephalosporins Protein synthesis inhibitors acting on ribosomes Cell membrane Sulfonamides (sulfa drugs) Cell wall inhibitors Penicillins Polymyxins Erythromycin Aminoglycosides Quinolones Folic acid synthesis DNA/RNA Rifampin
Fluoroquinolones, like Ciprofloxacin and Moxifloxacin. inhibit: protein synthesis. membrane cunction. DNA gyrase. enzyme function ax competitive...
Fluoroquinolones, like Ciprofloxacin and Moxifloxacin. inhibit: protein synthesis. membrane cunction. DNA gyrase. enzyme function ax competitive inhibitofs. cell wall synthesis Modified Thayer Martin (MTM) is a supplemented chocolate agar made selective for pathogenic Neisseria(S. gororrhoeae & N meninguidu) by addition of: Vitamins Antibiotics High NaCI (7.5% salt) Low pH High pH What is not tnie of capnophiks? mammalian cells in culture have a requirement for increased carbon dioxide Neisseria Hemophilus all of the above arc true The TCA cycle produces
Gram +ve Resistant Strains (%) 100 BOS Ribosome 90 50 Ribosome 80 Folate Pathway 70 DNA/RNA Synthesis 60 Cell Wall Synthesis Fell Membrane Synercid Antibiotic (20 kg/ml) Apramycin Gentamicin Neomycin Streptomycin Tetracycline Minocycline Tigecycline Clindamycin Chloramphenicol Gram -ve 100 305 Ribosome 90 505 Ribosome Folate Pathway 70 DNA/RNA Synthesis Cell Wall Synthesis Resistant Strains (%) Antibiotic (20 wg/ml) Erythromycin Telithromycin Linezolid Sulfamethoxazole Apramycin Trimethoprim Gentamicin Ciprofloxacin Neomycin Novobiocin Streptomycin Rifampicin Tetracycline Vancomycin Meropenem Minocycline Cefotaxime Tigecycline Cephalexin Clindamycin Fosfomycin Chloramphenicol...
Which antimicrobial drug has narrow spectrum of activity? Tetracyclines Chloramphenicol Streptomycin Vancomycin 12. Quinolones are synthetic antimicrobials that... Blocks folic acid synthesis Inhibit DNA replication Inhibit cell wall synthesis Affect the cell envelope
SUMMARY OF ANTIBIOTICS USED FOR KIRBY-BAUER DISK DIFFUSION SENSITIVITY Antiblotic Name Natural, Semi Spectrum of Activity: Active Against GP, Mechanism of Action* Side Effects/Other or Synthetce? Broad or Narrow? GN or both Vancomycin Erythromycin Sulfamethoxasole Trimethoprim Cefazolin Ciprofloxacin Ampicillir Oxacillin Gentamicin Ceftazidime Linezolid Daptomycin Ceftobiprole Cell wall synthesis inhibitor, protein synthesis inhibitor, disruptor of cytoplasmic membrane, metabolic pathway inhibitor, DNA/RNA synthesis inhibitor
2) List the major targets of an antimicrobial drug. What do all of these targets have in common? 3) Why is the Kirby-Bauer test standardized? 4) What is the advantage of the broth dilution tests for antibiotic sensitivity over the Kirby Bauer? 5) In general, why are Gram negative bacteria resistant to some of the antibiotics that Gram positive bacteria are sensitive to? 6) Fill in the following chart. ANTIBIOTIC CELLULAR TARGET AMPICILLIN CHLORAMPHENICOL ERYTHROMYCIN GENTAMICIN PENICILLIN STREPTOMYCIN TETRACYCLIN VANCOMYCIN
How do streptomycin and simlar antiblotics affect prokaryotic cells? 。These antibiotics interfere with peptidoglycan formation. O These antiblotics interfere with protein synthesls. O These antiblotics Interfere with DNA replication. O These antiblotics Interfere with cell wall formation. These antibiotics interfere with cell membrane integrity. 2. Why are eukaryotic cells unaffected by streptomycin and similar antiblotics? 0 Eukaryotic cells have organelles called lysosomes that engulf and break down these types of antibiotics. O Eukaryotic protein synthesis is not disrupted because these...
2) List the major targets of an antimicrobial drug What do all of these ta common? all of these targets have in 3) Why is the Kirby-Bauer test standardized? 4) What is the advantage of the broth dilution tests for antibiotic sensitivity over Kirby Bauer? 5) In general, why are Gram negative bacteria resistant to some of the antibiotics that Gram positive bacteria are sensitive to? 6) Fill in the following chart. ANTIBIOTIC CELLULAR TARGET AMPICILLIN CHLORAMPHENICOL ERYTHROMYCIN GENTAMICIN PENICILLIN...
Which of the following antibiotics is a cell wall inhibitor but is not a beta-lactam? Vancomycin а b Penicillin Cephalosporin d Monobactams Carbapenems е au Joshua, a cancer patient, is placed on the chemotherapeutic docetaxel and an additional drug that causes immunosuppression to decrease the possibility of hypersensitivity to the chemotherapeutic. Which of the following would this drug be? Corticosteroid a b Mineralcorticoid Gonadocorticoid C Antibiotics that work as protein synthesis inhibitors generally disrupt translation by working at the Enzyme...
Label the image to review major targets of drugs acting on bacterial cells. Cephalosporins Protein synthesis inhibitors acting on ribosomes Cell membrane Sulfonamides (sulfa drugs) Cell wall inhibitors Penicillins Polymyxins Erythromycin Aminoglycosides Quinolones Folic acid synthesis DNA/RNA Rifampin
Fluoroquinolones, like Ciprofloxacin and Moxifloxacin. inhibit: protein synthesis. membrane cunction. DNA gyrase. enzyme function ax competitive inhibitofs. cell wall synthesis Modified Thayer Martin (MTM) is a supplemented chocolate agar made selective for pathogenic Neisseria(S. gororrhoeae & N meninguidu) by addition of: Vitamins Antibiotics High NaCI (7.5% salt) Low pH High pH What is not tnie of capnophiks? mammalian cells in culture have a requirement for increased carbon dioxide Neisseria Hemophilus all of the above arc true The TCA cycle produces
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