Cells posses mechanisms to ensure that mis-folded proteins do not accumulate in the ER. Describe these mechanisms.
Cells posses mechanisms to ensure that mis-folded proteins do not accumulate in the ER. Describe these...
Processing of proteins is subject to quality control within the ER, which prevents improperly folded proteins from reaching the cell surface. What are the typical fates of the misfolded proteins and which proteins play a role in this process?
1. Describe how proteins are targeted and synthesized in the ER. 2. Describe nuclear pore transport. Why a pore and not a simple membrane translocator? 3. Describe how exocytose and endocytose vesicle targeting mechanisms.
Describe When and How Oligosaccharides are added to proteins in the ER.
In what conformational state do proteins cross the mitochondrial membranes? A. in fully folded (native) form. B. bound to an importin recognized by a signal sequence. C. in unfolded extended form without chaperones. D. in unfolded extended form attached to Hsp70 chaperones.
Describe the main mechanisms by which newly synthesized proteins are transported from the cytosol to mitochondria and outline the importance of signal sequences and protein processing in the localization of proteins within the different compartments of the mitochondrion.
Describe the mechanisms that confine cells and tissues to a specific anatomic site
Describe the molecular mechanisms responsible for HIV recognition of T helper cells (TH cells) and HIV import across the TH cells plasma membrane.
Describe the barriers, cells, and proteins involved in the different phases of the immune response
Describe the mechanisms that cells can use to make a nonspontaneous reaction spontaneous Describe metabolite activation and its role in metabolism brief explanation on each, please. No pictures or anything needed, basic concept works! thanks so much!!
Describe the potential mechanisms that are thought to be involved in how stems cells might ‘work’. Your ‘list’ may not be relevant to all stem cell types, or therapies, but you need to consider them all. (Hint: there are more than 3!)