will the results of an in vitro antibiotic sensitivity test always agree with the results of an in vivo use of antibiotic? why or why not?
No, tests or the invitro antibiotic sensitivity test will not always agree with the results of an in vivo use of antibiotic. This is because when the biomolecule to be targeted with the antibiotic, will have relatively different environment, so it's sensitivity will differ, also depends on the administration of the antibiotic IN vivo, if it is orally administered, it will pass through liver and by metabolic enzymes it is acted upon and it's function will change. According to the cells responding IN vivo when associated with other organs of cells of the immune system, antibiotic sensitivity may get change, and a little change in results can be expected.
will the results of an in vitro antibiotic sensitivity test always agree with the results of...
An antibiotic sensitivity test was performed for S. aureas, B.
cereus, E coli and S. typhimurim. The antibiotics used are
Gentamycin (GM), Chloramphenicol (C), Streptomycin (S), Ampicillin
(AM), Tetracycline (TE) and Erythromycin (E). The diameters of the
zones of inhibition were measured for each antibiotic and recorded.
S = susceptible. R = resistant. I = intermediate. Do the results
align with the expected results for each organism?
16 Name: Section Lab Report Date Observations and Results Part A: Kirby-Bauer Antibiotic Sensitivity Test Procedure 1. Record the zone size and the susceptibility of each test organism to the chemotherapeutic agent as resistant (R), intermediate (1), or sensitive (S) in the charts below. E coli P. vulgaris GRAM-NEGATIVE Paeruginosa Zone Size Susceptibility ACID-FAST M. smegmatis Zone Size Susceptibility Chemotherapeutic Zone Size Zone Size Agent Susceptibility Susceptibility Penicillin Streptomycin Tetracycline Chloramphenicol Gentamicin Vancomycin Sulfanilamide 32 32 GRAM-POSITIVE E. faecalis S....
[Antibiotic sensitivity Test] If you have a plate with no zones what does that tell you about the importance of this organism? Consider your response from both the patient and an epidemiological perspective. Have you heard of such a thing? Yes…..so give an example.
Using the Kirby-Bauer test to test antibiotic activity, what controls would you have?? From your results, how would you create a new antibiotic??
A new test was compared with a gold standard measurement with the following results Sensitivity Specificity Positive predictive value Negative predictive value New Test Gold Standard Positive Gold Standard Negative Positive 18 2 Negative 8 72
What is an E-test strip and are they more or less advantageous to use than the standard antibiotic sensitivity disks? Why? For which organisms are the E-test most useful?
You want to test the effects of different antibiotics on protein synthesis. You set up three test tubes to carry out protein synthesis in vitro. After letting protein synthesis proceed, you add the following to the tubes: Tube A - No antibiotic Tube B - Antibiotic B Tube C - Antibiotic C (1) Please state the results shown below. (2) Given the results, which step of translation may be most likely affected by Antibiotic B? Explain your answer. (3) Give...
explain why it is difficult to have a screening test that has 100% sensitivity and specificity. use labeled drawings as appropirate.
1. Interpret the following standard antibiotic test results using the interpretive chart below. Assume that the method was used correctly and that all antibiotic discs were effective (not expired): (5 marks) a. Aeromonas hydrophilia tested with Tetracycline had an average zone size of 16.5 mm b. Aeromonas hydrophilia tested with Pencillin G had an average zone size of 10 mm c. Staphylococcus aureus Patient AB tested with Pencillin G had an average zone size of 24 mm. d. Staphylococcus aureus...
2. Researchers in Israel have developed a novel method of restoring antibiotic sensitivity to resistant bacteria, according to a study in the journal Applied and Environmental Microbiology. The process could eventually be used to fight hospital superbugs, researcher said. An estimated 70% of hospital acquired infections in the U.S. involve bacteria that are resistant to at least one antibiotic. Using a process called lysogenization, scientists used bacteriophages, viruses that can infect bacteria, to invade resistant bacterial cells and restore their...