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will the results of an in vitro antibiotic sensitivity test always agree with the results of...

will the results of an in vitro antibiotic sensitivity test always agree with the results of an in vivo use of antibiotic? why or why not?

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No, tests or the invitro antibiotic sensitivity test will not always agree with the results of an in vivo use of antibiotic. This is because when the biomolecule to be targeted with the antibiotic, will have relatively different environment, so it's sensitivity will differ, also depends on the administration of the antibiotic IN vivo, if it is orally administered, it will pass through liver and by metabolic enzymes it is acted upon and it's function will change. According to the cells responding IN vivo when associated with other organs of cells of the immune system, antibiotic sensitivity may get change, and a little change in results can be expected.

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