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Hemidesmosomes and focal contacts are not found on the same cells at the same time. Why?

Hemidesmosomes and focal contacts are not found on the same cells at the same time. Why?
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Hemidesmosomes and focal contacts are not found on the same cells at the same time .because hemidesmosomes focal contacts play major roles in epidermal wound healing and in the pathogenesis of sub epidermal blistering diseases. it is of particular impact to understand their cross talk in the regulation of their assembly and disassembly .in this issue demanustrate that hemidesmosomes enriched protein complex and focal contacts dynamics are rightly coregulated in kerotinocyte undergoing migration by Hacat cells that Express proteins tagged B4 integration a- actinin markers of HPC nd FC.

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