Running the Reaction Add 0.100 g benzil and 0.30 mL 95% ethanol to a 3-mL conical vial. Place a s...
Place 3.0 g of salicylic acid in a 125-ml Erlenmeyer flask. Carefully add, stirring constantly, 6 mL of acetic anhydride, followed by 10 drops of concentrated sulfuric acid. Swirl the contents of the flask so that the reactants are thoroughly mixed. Stopper the flask with a one- hole cork fitted with an inverted Pasteur pipet to prevent condensation of water in the reaction flask during heating on the steam bath. Heat the flask in a boiling-water or steam bath for...
QUESTION: Write a flow scheme for the work-up. THE WORK UP: C. Work-up (save all layers) and Isolation of Product MgBrCl Benzoic acid Transfer the mixture into a test tube. Rinse the beaker with about 3 mL of regular (not anhydrous) diethyl ether and pour the washings into the test tube. There should be two distinct layers in the test tube Remove the aqueous layer (to be discarded) and shake the ether layer with about 2 mL of 3 M...
1.) What side reactions occur during the following steps. 2.) How can the IR spectrum be used to show that there is not starting material left and the products are ketones? 3.) Describe the major differences and similarities between the IR spectra of benzoin and benzil. Compare your IR spectrum with those of benzoin and benzil. Copper-Catalyzed Oxidation of Benzoin 1. Add a stir bar and 1.5 mL of glacial acetic acid, 0.250 g of NH4NO3 and 0.500 g of...
used. Experimental . Place 2.0 g of salicylic acid in a 125-mL conical flask. 2. Add 4.0 ml (d = 1.08 g/mL; 4.3 g) of acetic anhydride and 6-8 drops of 85% phosphoric acid. 3. Swirl the flask to mix all reagents, and place it in a 70°C water bath. Heat for about 10 minutes. 4. Remove the flask from the water bath and add 2 mL of cold water drop- wise, swirling the flask after each addition, 5. Add...
Write out your separation scheme for this experiment. 1. Heat 75 mL of water to 90 °C in a 250-mL beaker. 2. While the water is being heated, place 250 mg of salicylic acid, 1 drop of 85% phosphoric acid and 0.5 mL of acetic anhydride in a test tube. Add a boiling chip to the mixture and gently shake it in order to mix the reactants. 3. Heat the tube in the beaker of water at 85 - 90...
Draw a pathway for the reaction of phenylboronic acid with 4-iodophenol to obtain 4-phenylphenol in the form of a catalytic cycle. EXPLAIN and STATE all complexes formed in EACH STEP by their electron counts (count how many e- are there, e.g. 18 e- or 16 e- etc.), formal oxidation states and all the reactions with mechanistic labels (i.e. oxidative addition, reductive elimination, etc.) (note the amount of base used). Be sure to EXPLAIN the catalytic cycle as to what happens...
Can you explain how to find what is the theoretical yield, and the desired percent yield of ethyl 4-nitrobenzoate? 1. Synthesis of ethyl 4-nitrobenzoate a) In a 50-ml round-bottom flask, weigh out 4-nitrobenzoic acid (0.85 g, 0.005 mol). Add to this 8 ml of absolute ethanol. Add boiling stones, and then bring this solution to the Lab Technologist. WATER OUT b) The Lab Technologist will deliver 1.2 ml of concentrated sulfuric acid to the mixture from the automatic pipette. [CAUTION,...
PROCEDURE 1. Place a reaction tube into a 5-mL Erienmeyer and tare. Add between 0.275- 0.300g of salicylic acid. Record on the data sheet. 2. Transfer the reaction tube and 5-ml Erienmeyer to the hood. Add a boiling chip, 2 drops of 85% phosphoric acid, and about 0.70 mL of acetic anhydride to the reaction tube. Mix well. 3. Place a 50-ml beaker containing about 20-mls of water on a hot plate or in the sand bath. Allow the water...
What is the mechanism (with curved arrows) for this reaction? 1. Add about 1.0 g (measured accurately) of acetophenone to 40 mL of the bleach solution (5% NaCl in water - this reactant should be included in your table of reagents!) in a 100 mL round bottom flask equipped with a magnetic stirrer. Clamp the flask in the fume hood above a stir plate. 2. After the initial reaction has subsided, boil the reaction mixture gently for 5 - 10...
Bromination of Acetanilide In a 25-mL Erlenmeyer flask, dissolve 0.68 g of acetanilide in approximately 4 mL glacial acetic acid. Record the exact amount of the limiting reactant that you used. Add a stir bar followed by 1.6 g pyridinium tribromide. Heat the mixture to ~60°C in a warm water bath for 10 minutes. After the 10 minutes, add 15 mL water and approximately 2 mL saturated sodium bisulfite solution to remove excess bromine, which shows by the disappearance of...