Explain how a tissue-specific RNA-binding protein can lead to tissue-specific alternative splicin...
Explain how a tissue-specific RNA-binding protein can lead to tissue-specific alternative splicing via splicing enhancers or splicing silencers.
| A.Trans-acting sequences that promote (splicing enhancers) or inhibit (splicing silencers) splicing are recognized by different classes of RNA-binding proteins (RBPs). |
| B. Trans-acting sequences that promote (splicing silencers) or inhibit (splicing enhancers) splicing are recognized by the same class of RNA-binding proteins (RBPs) in different tissues. |
| C. Cis-acting sequences that promote (splicing enhancers) or inhibit (splicing silencers) splicing are recognized by different classes of RNA-binding proteins (RBPs). |
| D. Cis-acting sequences that promote (splicing silencers) or inhibit (splicing enhancers) splicing are recognized by the same class of RNA-binding proteins (RBPs) in different tissues. |
Homework Answers
The answer is A.Trans-acting sequences that promote (splicing enhancers) or inhibit (splicing silencers) splicing are recognized by different classes of RNA-binding proteins (RBPs).
Since trans-acting sequences are those which are synthesized at a location other than the gene they're going to act on, they are recognized by different classes of RBPs.
Also, the sequences that promote splicing are enhancer and those which inhibit splicing are splicing silencers.
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explain figure 2 please on the third page
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