Please point out whether each of the following statements is correct or not. Carefully explain your reasoning! a) In Asp...
Please point out whether each of the following statements is correct or not.
Carefully explain your reasoning!
a) In Aspartic Acid, the carboxylic group bound to the α carbon has more acidic properties than the carboxylic group that is located in the side chain.
b) The pI of Ala-Gly-Met is 6.0.
c) The peptide Ile-Ala-Pro is more hydrophilic than the peptide Gln-His-Ala.
d) The side chain of Amino Acids that make up a protein function as a buffer.
thank you :)
Homework Answers
a) Correct
Explanation: The pKa value of the side-chain COOH = 3.9, that of α-COOH = 3.5
Lesser the pKa, the greater is the acidic nature because of pKa = -Log(Ka)
b) Correct.
Explanation: pI = (3.5 + 9)/2 = 6.25
c) Incorrect.
Explanation: The peptide Gln-His-Ala is more hydrophilic than the peptide Ile-Ala-Pro.
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