Are these right? If not, what needs to change?
the possible reagents and the product conversions are
based on the reactants are as follows
Are these right? If not, what needs to change? Br weak base /weale nucleophile LOEL + enantiomer
strong nucleophile weak base strong bulky base strong nucleophile strong base Promote SN2/E2 weak nucleophile weak base Promote SN1/E1 Promote SN2 Promote E2 CH Br HS NCT HO CHO CHÚCHO NaNO NaOH NOME Noe HOORS Conjugate acids have pka 16-18 Conjugate acids Recall, you make hydroxide have pka 11 or alkoxide ons from the corresponding alcohol or water and Nat CH,OH (MOH) HO CH,CH,OH (EXOH) | HC-Ć-o to CH tert-BUOK NOCH KOHBU NEOBU The structures above are all ways of...
Why is NC- a good nucleophile? and why is it a weak base?
What is the product of this reaction? Br2 Н,0 +enantiomer o Br '+enantiomer ООН + enantiomer о он Br+enantiomer
How can you tell if a reactant, like the NaOH, is a strong/weak nucleophile or base to determine what mechanism you use? The picture provided has the correct answers. I just don't understand how to get to them. 3. Draw a structural formula for the major organic product(s) of each reaction and specify the mechanism by which each product is formed (SN1, S2, E, or E2). E2 NaOH Н,0 CH3CH2ONa CH3CH2OH E2 CH2ONa иис CH3OH OCH3 Br CH3OH ИИ E1...
How can you tell what is a weak/strong nucleophile and a weak/strong base to determine what mechanism you use (SN1, SN2, E1, E2)? 3. Draw a structural formula for the major organic product(s) of each reaction and specify the mechanism by which each product is formed (SNI, SN2, El, or E2). NaOH HO CH2CH ON CH3CH OH CHON CH,OH CH,OH DMSO
Questions about nucleophile.. I heard that, down a column, it's good nucleophile but.. generally, strong base is strong Nu (exept for solvent issue) and 'As' (from AsH3) is more polarizable than 'P' (from PH3) thus, i think, As is to weak base(since it is stable) and P is more strong.. but it's not. why?
ndyla S Chapter 7 (Snl-Sn2-E1-E2) Revie w +Problems 1°Leaving group (example): Br React with the following reagents (Strong base /strong nucleophile) B) I, NC, Na (Strong nucleophile/ weak base) C) H (NaH or Ca) tBuO/tBuOH (Strong base/non- nucleophile) D) H:0, ROH, RCO2H Weak nucleophile/ very weak base- even acidie "Solvolysis" - type reactions P 2010 2° Leaving group (example): (sometimes "hindered") Ri React with the following reagents (Strong base / strong nucleophile) B) I, NC. N (Strong nucleophile/ weak base)...
SN 2: Mechanism: Br NaOH E2: Mechanism: Br NaOH 20 30 Methyl 1° Strong Weak 30 Preferred Alkyl Halides: Preferred Nucleophiles: Product Stereochemistry: Methyl 1° Strong 2° Weak Preferred Alkyl Halides: Preferred Base: Reagent Stereochemistry: Product Regiochemistry: Sw1: Mechanism: ~ Br H2O E1: Mechanism: Br H2O Preferred Alkyl Halides: Methyl 1° 30 20 Preferred Alkyl Halides: Preferred Nucleophiles: Product Stereochemistry: Methyl 1° Strong 20 Weak Weak Strong Preferred Base: Product Regiochemistry:
supply the arrows for each of the following reactions. Identify the nucleophile/base and the nucleophile/acid (when possible). Calculate ΔH for each reaction. Estimate (>1 or <1 )for each reaction. Is the reaction exothermic or endothermic ? to c redit the band that provided Uploader with your name dy showWORD POETEG HCl + HC NH • HCH, LusRegee.blackboard.com Question Completion Star Reaction 1 H3C + HAC-NH2 нсны :: HC CH the lörleri HyCCH Br | + Brt NH NH2 Attach Fle...
what are the products for the following reactions? 1.) Br2 2.) heated KOH Br OH Br enantiomer enantiomer A B с D HBr HOOH Br Br enantiomer Br enantiomer A B С D