EtOH heat NaOH DMSO NaCN DMF Jones reagent reagent(s) OAC reagent(s); reagent(s); reagent(s);
ETOH -Br heat - Br k. NaOH DMSO NaCN Br DMF m. OH Jones reagent
1. Predict the product(s) (or no reaction) and reagent(s). j. ETOH Br heat k. Br NaOH DMSO NaCN Br DMF m. РСС Н n. О H2SO4, H20 Н
1. Predict the product(s) (or no reaction) and reagent(s). (17 pts) KI DCM ЕТОН heat H2O heat DBU DCM Testos e sot KNE DMF KOME DMF KOET HMPA LDA THF NaO'Bu toluene EtOH heat NaOH DMSO NaCN reagent(s); OH reagents) reagents):
Conditions Starting Material Major Product(s) OH PBrg Et20 NaCN DMF OMs NaNH2 DMSO, 20'C 8 hr 1) NaH, DMF, -78°C 2) A ci NaOH Br OH
Starting Material Conditions OH PBr3 Eto C NaCN OMs DMF Br NaNH DMSO, 20°C 8 hr 1) NaH, DMF, -78°C 2) A ci NaOH
1. Predict the product(s) (or no reaction) and reagent(s). (17 pts DCM EtOH heat BU DCM Br tot & ob 8 6 6 KN, DMF Коме DMF ΚΟΕΙ HMPA LDA THF NaO Bu toluene
4. Determine if Syl or Sn2 and the product formed. CH3OH CH3OH CH,OH CH3OH өОН DMF өОН 1112 DMSO NaCN DMSO
Predict the product & reagent. -Br ki DCM EtOH heat &송당송당 H2O heat DBU Br DCM KN3 DMF
Question 39 3.3 What is the best choice of reagent(s) to perform the following transformation? H2O, H2504 Hg(OAc)2 and H20;followed by NaBH4 BH3; followed by H2O2. NaOH OsO4: followed by NaHSO3 Question 40 3.3 Which of the following sets consists of only aprotic solvents? water, hexane, methanol acetic acid, DMF, toluene DMSO, ethanol, acetonitrile hexane, acetonitrile, DMSO
a. B2H6, diglyme b. NaOH, H202 c. MsCl, py d. NaCN, DMSO