Question

. 17. A loading dose of acetylcysteine (Mucomyst) 8 grams, which is available as a 20% solution (200 mg acetylcysteine per ml) is prescribed by nasogastric tube for a client with acetaminophen toxicity. How many ml of diluent should be added to the medication to obtain a 1:4 concentration? (Enter numeric value only. If rounding is required, round to the nearest whole number.) 18.A child who weighs 55 pounds receives a prescription for atovaquone with proguanil (Malarone Pediatric) 125 mg/50 mg PO daily. A drug reference states that children 11 to 20 kg should receive 1 pediatric tablet daily; 21 to 30 kg should receive 2 pediatric tablets daily; 31 to 40 kg should receive 3! pediatric tablets daily; and greater than 40 kg should receive 1 adult tablet daily with food. The drug is available as atovaquone 62.5 mg/proguanil 25 mg pediatric tablets. How

Answer 1

Please find answer below.

1 mL contains 200mg drug.

Loading dose is 8grams. Hence 40 mL is required.

for 1:4 Ratio, 40mL drug solution (acetylcysteine) should be added to 160mL diluent. (40:160)

Answer is 160mL diluent.