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4. The pyruvate dehydrogenase complex catalyzes a multi-step reaction. The key product, acetyl-CoA is released after...
The pyruvate dehydrogenase complex catalyzes a multi-step reaction. The key product, acetyl-CoA is released after the third step. What is the purpose of the remaining steps?
The step in metabolism that converts pyruvate to acetyl-CoA involves pyruvate dehydrogenase complex is shown. NADH NAD Correm A CEO CH co G Pyruvate AwA What is true about this step? ATP is required but not shown The enzyme is a multi-enzyme complex involving TPP. It requires O2 It is an easily reversible reaction
1. The pyruvate dehydrogenase complex converts pyruvate to acetyl-CoA. What are the steps that pyruvate undergoes? Which coenzymes are involved in each step? 2. Mitochondrial extracts from pigeon breast muscle were incubated with Experiment 1: Amytal, an inhibitor of complex I Experiment 2: Malonate, a competitive inhibitor of succinate dehydrogenase Which experiment will yield more ATP when the cycle is primed with intermediates?
Why does acetyl CoA, a product of fatty acid catabolism, influence the pyruvate dehydrogenase complex (PDH), a control point in carbohydrate catabolism? When fatty acid breakdown is high, ADP is low and PDH is inhibited by phosphatase activity. When fatty acid breakdown is inhibited, PDH is inhibited by acetyl CoA due to phosphatase activity. When fatty acid breakdown is high, NADH levels drop, causing an increase in E2 activity. When fatty acid breakdown is high, PDH is inhibited by acetyl...
1.Predict the effect of a large amount of acetyl-CoA on the activity of pyruvate dehydrogenase and the rate of glycolysis. Note: pyruvate dehydrogenase is the enzyme that catalyzes the formation of acetyl-CoA from pyruvate. a. Pyruvate dehydrogenase activity will decrease while the rate of glycolysis will increase. b. Both pyruvate dehydrogenase activity and the rate of glycolysis will decrease. c. Pyruvate dehydrogenase activity will increase while the rate of glycolysis will decrease. d. The rate of glycolysis will increase, thereby,...
4. (20 points) The reaction of pyruvate to acetyl-CoA and CO2 is the bridge reaction between glycolysis and the citric acid cycle. The carbon atoms in pyruvate are numbered and where they end up in the products are indicated CO0Θ 2 C=O + HS-CoA 3 CH3 Pyruvate S-COA 2C=O 3 CH3 Acetyl CoA Pyruvate dehydrogenase +1 CO2 a) Is C atom 1 in CO2 in a more reduced state or more oxidized state compared to its state in pyruvate? Why?...
QUESTION 2 The pyruvate dehydrogenase complex O a. leads to the formation of coenzyme A (COA). Ob.catalyzes key reactions in glycolysis. Oc oxidizes NADH to NAD+. d. can be found in the mitochondria of eukaryotic cells.
I1. Mammals lack the enzyme a. Lactate dehydrogenase b. Pyruvate kinase Alcohol Dehydrogenase c. d. Pyruvate decarboxylase None of the above are correct e. 12. The first reaction of the Krebs cycle combines Oxaloacetate and Acetyl CoA to make Citrate b. a. Malate and NADH to make Citrate a-ketoglutarate and citrate to make CO2 d. c- Succinate and Citrate to make Oxaloacetate 13. The electrons held by NADH and FADH, are donated to the which complexes in the ETC respectively?...
8. Draw the overall coupled reaction showing the conversion of pyruvate into acetyl CoA. dono STEP 2 nach do not ww what are true. Ir raise, change one word in the statement so that it is true. a. The pyruvate produced from glycolysis must be consumed in some way or glycolysis stops. b. Glycolysis produces ATP directly. too C. Glycolysis breaks down glucose into acetyl CoA. d. Glycolysis is aerobic
How many CO2 molecules are released if 2 molecules of glucose are catabolized to acetyl-CoA via the reactions of glycolysis and pyruvate dehydrogenase? a) 4 b) 6 c) 2 d) 1 e) 12