Question

What the major product when p-Fluoroanisole reacts with sulfur trioxide and sulfuric acid? Draw the major...

image from custom entry toolWhat the major product when p-Fluoroanisole reacts with sulfur trioxide and sulfuric acid? Draw the major product of this substitution reaction; if applicable, minimize formal charges via expanded octets. Assume 1 equivalent of reagents is used.

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Answer #1
Concepts and reason

This problem is based on the concept of sulfonation reaction of aromatic compounds.

Aromatic compounds undergo a chemical reaction in the presence of fuming sulfuric acids and sulfur tri oxide with sulfuric acid in order to form a sulfonated product. This reaction is called sulfonation.

Fundamentals

In the sulfonation reaction of an aromatic compound, a sulfonyl group is substituted at the benzene ring in order to give sulfonic acid.

Structure of the reactant is given below:

CH3
F

The sulfonation reaction of p-fluoroanisole is given below:

CHз
CHз
OH
H2SO
4
F
F
5-fluoro-2-methoxybenzene-1-sulfonic acid
O=S=[
+

Ans:

The major product of the reaction is as follows:

CН3
НО
F
о-30

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