Problem

In a mixed copolymer experiment using polynucleotide phosphorylase, 3/4G:1/4C was used t...

In a mixed copolymer experiment using polynucleotide phosphorylase, 3/4G:1/4C was used to form the synthetic message. The amino acid composition of the resulting protein was determined to be:

From this information,

(a) indicate the percentage (or fraction) of the time each possible codon will occur in the message.

(b) determine one consistent base-composition assign men for the amino acids present.

(c) in view of the wobble hypothesis, predict as many specific codon assignments as possible.

HINT: This problem asks you to analyze a mixed copolymer experiment and to predict codon composition assignments for the amino acids encoded by the synthetic message. The key to its solution is to first calculate the proportion of each triplet codon in the synthetic RNA and then match these to the proportions of amino acids that are synthesized.

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