The number of clones needed to screen a yeast genomic library at 99% confidence
Yeast(Saccharomyces cerevisiae) has a genome size of 1.21 x 107 bp. If a genomic library of yeast DNA was constructed in a bacteriophageλvector capable of carrying 16 kbp inserts, how many individual clones would have to be screened to have a 99% probability of finding a particular fragment?
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