Understanding the very tight binding of transition states
Another consequence of tight binding (problem 9) is the free energy change for the binding process. Calculate ΔG°’ for an equilibrium with a KD of 1×10-27 M. Compare this value to the free energies of the noncovalent and covalent bonds with which you are familiar. What are the implications of this number, in terms of the nature of the binding of a transition state to an enzyme active site?
We need at least 10 more requests to produce the solution.
0 / 10 have requested this problem solution
The more requests, the faster the answer.