Question

The process of dynamic eqilibrium determines drug concentration in the body. Describe how the phases of absorption, distribution, metabolism, and excretion impact drug concentrations.

Answer 1

In the body drug concentration depends many factors which are =

Drug solubility

Drug concentration

Route of drug administration

Amount of drug administration

Form of drug

Absorption of drug

Metabolic state of live

And excretion by kidney

2 various how to effect ___=====

Absorption = any drug concentration depends on rate of absorption such if drug give orally or gastro system then absorption every slow and requires more dose to desire effect then other route and I/v route not requires to absorption

Distribution = if blood supply is good then drug distribution is comparing good

Metabolism = metabolism depends on the workingcondition of the liver it's good then metabolism is good

Excretion= any drug excrete from body various route such as sweat ,bile ,urean but kidney play an important role in drug excretion and which depends on kidney condition ,blood supply, hydration of body ,solubility of drug