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an individual is deficient in complement component c3 describe the consequences of this deficiency in MAC

an individual is deficient in complement component c3 describe the consequences of this deficiency in MAC

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c3 is required for opsonisation(coating of pathogenic cells with opsonin to facilitate phagocytosis).Deficiency of c3 can lead to problems with opsonisation.

The consequences of complement component c3 deficiency in MAC can lead to recurrent infections with encapsulated organisms with sequelae and high morbidity and mortality .There may be overwhelming sepsis in early life .It can cause autoimmune disorders.

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