Question

HULUH Dallerld. 8. Many antibiotics inhibit protein synthesis. They should be narrow or broad spectrum antibiotics and why? Name 3 of them and explain how/where they work (site of action). 9. Usually, how many ways bacteria becomes drug resistance-explain. 10. What is Kirby-Bauer test and what it is used for? Explain the process. 11. Why animal viruses have envelope, explain with example. 12. What is the basic difference between infection by phage and an animal virus, explain? 13. Can we culture virus like we do with bacteria in media? What are the ways virus is cultured-explain? 14. Why it is difficult to design drugs for virus? Name two anti-virus drugs and explain how they work. 15. What is prion? What it causes, explain.

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Answer 1

PAGE NO.: DATE: - Ans 38 Antibiotics that inhibit Protein Synthesis are Tetra Cycline Doxycycline Streptomycin Gentamycin Erythromycin Kanamycin some antibitics are narrow Spectrum means they can be used only for specific infections or diseases and some are broad Spectrum means they can be used for many infections or a - number of diseases. Wook of action of protein inhibitors. These antibiotics inhibit Protein Synthesis by a number of ways. such as In Ribosome there are two subunits! 305 and 50s and these anti- biotics inhibit the binding of I these Subunits that Prevent elongation and I Peptide Synthesis of new chain.

PAGE NO.: DATE: 1 Some antibiotics inhibit the enzyme required for Protein Synthesis that is peptidyl transferase these antibiotics also Prevent the binding of 30s ribosome with both 70s and 80s ribosomes that Prevent protein synthesis.