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Explain all the different mechanisms by which both narrow and broad spectra antibiotics destroy bacteria.

Explain all the different mechanisms by which both narrow and broad spectra antibiotics destroy bacteria.

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Answer #1

Whether narrospectrum or broad spectrum antibiotics the mechanism of bacterial destruction are as such:

  • Inhibition of the bacterial cell wall synthesis (made up of N-acetyl-D-glucosamine and N-acetylmuramic acid and thus disturbing the integrity of bacterial cell)
  • By inhibition of essential bacterial cell protein required for the growth and living of the bacteria
  • By inhibition of bacterial membrane functioning
  • By inhibition of nucleic acid synthesis by acting of 50S or 30S ribosome (in case of gentamycin) as well as by destructive action on t-RNA of bacteria causing bacterial growth inhibition or death like in case of choramphenicol
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