Homework Answers
The longer the half life the longer the intervals between administering the drug.A drug administered every 4 hours has a shorter half life than a drug administered every 12 hours.
Half life refers to how long it takes for a drug for half of its doe to be metabolized and eliminated from blood stream.Drug with longer half life takes longer to work and take less time to leave body
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13. The the half-life the the intervals between administering the drug. A drug administered every 4...
A new drug is started with a half life of 12 hours. If the drug is...
A new drug is started with a half life of 12 hours. If the drug is given every 12 hours, how many hours before the drug level in the body will reach a plateau?
(a) If a patient takes a 100 mg dose of a drug A (with half-life of...
(a) If a patient takes a 100 mg dose of a drug A (with half-life of 4 hr) every 4-hr, how much drug would be remain in the body at 24-hr (6 half-lives later)? Show work time 0 4 8 12 16 20 24 dose administered 100 mg 100 mg 100 mg 100 mg 100 mg 100 mg 100 mg total drug remaining in body 100 mg
When a 120 mg IV-Bolus of Drug A is administered to a patient, an AUC -60...
When a 120 mg IV-Bolus of Drug A is administered to a patient, an AUC -60 mg/L/hr is observed. Knowing that Drug A has an half-life of 12 hours, calculate the volume of distribution of Drug A in liters
If this drug has a half-life of 8-hr instead of 4-hr, what is the amount of...
If this drug has a half-life of 8-hr instead of 4-hr, what is the amount of drug in the body at 24-hr and 48-hr? time 0 hr 8 hr 16 hr 24 hr 32 hr 40 hr 48 hr drug administered 100 mg 100 mg 100 mg 100 mg 100 mg 100 mg 100 mg drug remaining 100 mg ? ? ? ? ? ?
Soru 18 Administering a drug sublingually has all of these advantages, except that the drug: is...
Soru 18 Administering a drug sublingually has all of these advantages, except that the drug: is absorbed rapidly immediately enters the bloodstream bypasses the liver and intestinal wall is swallowed D Soru 19 What does 6 gtt q8 hours mean? 6 ce's every 8 hours 6 drops every hours 6 drops after 8 hours 6 sprays as needed every hours Soru 20 | 3 4 5 6 7 8 9 0 D F G H J K L
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by...
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
Typical pharmacokinetic parameters of DRUG-A are F-0.02; fex < 0.1; fu 0.3; V- 0.22 L/Kg Half-life...
Typical pharmacokinetic parameters of DRUG-A are F-0.02; fex < 0.1; fu 0.3; V- 0.22 L/Kg Half-life 4 hours. Drug-A is administered as a continuous IV-Infusion to a patient taking another medication that is known to induce the hepatic-metabolism of Drug-A. Therefore, the time to reach steady state will: D Increase 0 Decrease O Show little difference
13. Aspirin is a common anti-inflammatory medication. A drug dose was administered orally and initial concentration...
13. Aspirin is a common anti-inflammatory medication. A drug dose was administered orally and initial concentration of Aspirin in plasma was 33.2 mg/L. Knowing that Aspirin elimination follows zero order kinetics and drug half-life is 15 min. Determine: How long will it take for a drug concentration to decrease to 5% of its initial value? What is the elimination rate constant?
Drug A has an half-life of 12 hours and a volume of distribution of 80 L....
Drug A has an half-life of 12 hours and a volume of distribution of 80 L. How many mg of drug are in the body when the plasma concentration is 0.4 ug/mL?
kinteic Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient...
kinteic
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
When a 120 mg IV-Bolus of Drug A is administered to a patient, an AUC -60 mg/L/hr is observed. Knowing that Drug A has an half-life of 12 hours, calculate the volume of distribution of Drug A in liters
Soru 18 Administering a drug sublingually has all of these advantages, except that the drug: is absorbed rapidly immediately enters the bloodstream bypasses the liver and intestinal wall is swallowed D Soru 19 What does 6 gtt q8 hours mean? 6 ce's every 8 hours 6 drops every hours 6 drops after 8 hours 6 sprays as needed every hours Soru 20 | 3 4 5 6 7 8 9 0 D F G H J K L
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
Typical pharmacokinetic parameters of DRUG-A are F-0.02; fex < 0.1; fu 0.3; V- 0.22 L/Kg Half-life 4 hours. Drug-A is administered as a continuous IV-Infusion to a patient taking another medication that is known to induce the hepatic-metabolism of Drug-A. Therefore, the time to reach steady state will: D Increase 0 Decrease O Show little difference
13. Aspirin is a common anti-inflammatory medication. A drug dose was administered orally and initial concentration of Aspirin in plasma was 33.2 mg/L. Knowing that Aspirin elimination follows zero order kinetics and drug half-life is 15 min. Determine: How long will it take for a drug concentration to decrease to 5% of its initial value? What is the elimination rate constant?
Drug A has an half-life of 12 hours and a volume of distribution of 80 L. How many mg of drug are in the body when the plasma concentration is 0.4 ug/mL?
kinteic
Case 1 ( homework) A drug (200 mg) is administered to a 70-kg male patient by multiple IV injections at 6-h intervals. The drug is water-soluble and has a distribution volume equivalent to that of total body water (50 liters). The drug has a biological half-life of 6 h. Calculate (Css (max), Css (min) and Cav(ss). The time necessary to reach 95% of the steady-state concentration. The number of doses required to reach 95% of the steady-state concentration.
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