Question

Acute inflammation involves a variety of cell types, including most cells, endorhelial cells, neutrophills, macrophages, and fibroblasts.communication and coordination aming these cells is affected by

A. antibidies

B. Molecule mediators of inflammation

C. the coagulation cascade

D. chemotaxis

Practice Questions 61 15. A patient had a bone marrow transplant and numerous blood transfusions during the course of treatment for cancer. A bone marrow biopsy performed to monitor for recurrence a few weeks after treatment ended, showed abundant hemo- siderin within macrophages. In this case, hemo- siderin accumulation is not likely due to A. deposition of immunoglobulin light chains produced by the patient's cancer. B. brown atrophy. C. excess dietary lipid. D. iron overload from blood transfusions. 16. Which of the cardinal signs of inflammation can be attributed to events that occur during the vas- cular phase of inflammation: A. Redness and swelling B. Redness and pain C. Heat and swelling D. Heat and pain 17. A patient with Crohn's disease of the intestine develops small lesions in the mouth that look like the surface mucosa has been eroded. These are best described as A. Abscess B. Empyema C. Cellulitis D. Ulcer 18. A biopsy is taken of the bronchus of a man who has smoked for 20 years. He has a chronic cough and a new lesion in the lung, concerning for can- cer. The pathologist describes "squamous meta- plasia" in the histologic appearance of the tissue. What does this finding imply? A. Chronic irritation induced the columnar tis- sue to develop into squamous tissue. B. Squamous tissue from the mouth has colo- nized the bronchus. C. Cancer is not yet present, but will inevitably develop D. The process is irreversible. 19. Acute inflammation involves a variety of cell types including most cells, endothelial cells, neutrophils, macrophages, and fibroblasts. Communication and coordination among these cells is affected by A. antibodies. B. molecular mediators of inflammation. C. the coagulation cascade. D. chemotaxis. 20. A woman who just had a routine screening mam- mogram is advised to undergo a biopsy because calcifications were seen on the radiographic images. Why do calcifications in this setting indi- cate that cancer may be present? A. Some cancers can produce bony tissue. B. Some cancers release calcium into the blood, which can precipitate in diverse tissues, C. Some cancers interfere with normal calcium metabolism, so calcium is released in abnor- mal amounts in interstitial tissue. D. Cancers are associated with increased cell death, and calcium binds to the residue of necrotic cells. 21. The arachidonic acids metabolites are produced from A. the cell membrane lipids of leukocytes, endo- thelial cells, and platelets. B. enzymes within specialized organelles within neutrophils that aid with digestion of phago- cytosed material. C. the liver, and circulate in inactive form in the blood. cell membrane lipids of mast cells, and stored in granules until there is a stimulus for their release. 22. Plasma-derived molecular mediators of inflam- mation include all of the following except A. compliment proteins B. coagulation proteins C. chemokines and cytokines D. proteins of the kinin system

Answer 1

Inflammation is the process by which repair takes place when injury to living tissues occur. It may be acute or chronic depending on number of days inflammation continues. To start inflammatory process, many cells are required. They move towards site of injury by chemical substances that are diffused from area of tissue damage and make a concentration gradient. These substances are called chemotactic factors and one way migration of cells is called chemotaxis. So the process of chemotaxis is responsible for communication and coordination among these cells.