you need to calcukate a maintenance dose in mg for oatient (90kg) to target an average...
Homework Answers
Weight of the patient is 90kg
Average steady state concentration(desired peak concentration of drug ) Cp = 5mg/L
Bioavailability (F) of the drug is 86%
Clearance is 0.08 L/hr/kg
Calculate the maintenance dose :
Formula : MD = CpCL/ F
= 5mg/L × 0.08L/hr/kg ÷ 86
= 5 mg × 0.08 /hr /kg ÷ 86
= 0.0046 mg /hr/kg
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