Question

Consider a population with two autosomal alleles A, a, in Hardy-Weinberg equilibrium Let p and q be the allele frequencies of A and a, respectively 5. For what values ofp does the population contain more heterozygotes than any other genotype? Show all your working

Answer 1

Two autosomal alleles A ,a

p and q are allele frequencies of A and a

Hardy Weinberg equilibrium states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.

Hardy Weinberg equation is p^{​​​​​​2} + 2pq + q^{​​​​​​2} = 1

p^{​​​​​​2} = frequency of homozygous dominant genotype

2pq = frequency of heterozygous genotype

q^{​​​​​​2} = frequency of homozygous recessive genotype