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Introduction of naked dsRNA in humans evokes an immune response which shreds the RNA. Conceptually discuss...

Introduction of naked dsRNA in humans evokes an immune response which shreds the RNA. Conceptually discuss how you could administer a potential RNAi drug that might cure breast cancer?

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Generally dsRNA are immunogenic and causes immune system to activate but some ncRNA are involved in post-transcriptional control of gene. In this type some ncRNA are bound to form RISC and which then bind with arganote and directed towards target mRNA. And the target mRNA is cleaved into frangments and gene expression is controlled.

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