Which of the following could lead a mutation to express a dominant phenotype? Check all that...

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Which of the following could lead a mutation to express a dominant phenotype? Check all that...

Which of the following could lead a mutation to express a dominant phenotype? Check all that apply.

A) Both mutant and wildtype alleles are expressed in parallel in the phenotype

B) The mutant protein interferes with the function of wildtype protein

C) The affected gene is haploinsufficient

D) The affected gene is haplosufficient

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Answer 1

Answer #1

Ans :- B and D

If the mutant protein interfere with the function of wild type allele then the wild type phenotype can no longer be present in the population. This leads to mutant phenotype being dominant.

Haploinsufficient means if mutation takes place in one of the alleles then the other normal allele is not able to produce a functional protein thus the normal (wild type) phenotype does not appear. In this condition the mutated allele will be dominant.

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Answer 2

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