Use the Hardy-Weinberg equations (p^{2} + 2pq + q^{2} = 1 and p + q = 1) to find the genotypes of the following hypothetical phenotypic information:
a. Within a particular population, you observe that 450 individuals have freckles (dominant, F) and 550 do not have freckles (recessive, f).
b. Homozygous dominant (frequency) ______(A)_________
c. Heterozygous (frequency) ______(B)_____________
d. Homozygous recessive (frequency) _______(C)____________
Answer:
Frequency of freckles = q^2= 550/1000= 0.55
Frequency of recessive allele =q= sqrt of 0.55= 0.74
Frequency of dominant allele= p=1- 0.74= 0.26
Frequency of Homozygous dominant= pp= 0.26*0.26= 0.07
Frequency of heterozygote =pq= 2*0.26*0.74= 0.38
Frequency of Homozygous recessive= 0.74*0.74= 0.55
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