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A mutation occurs that causes the promoter of a gene to over-express a protein. Would this most likely be a gain of function
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This is due to the loss of the function mutation . The main function of the promoter gene is the regulation of the process of transcription . The promoter gene is present before the the start codon about - 35 in the 3' direction. The promoter have a binding site for the regulatory protein. Regulatory protein binds to the promoter gene and regulate its function . If a regulatory protein have a negative effect and inhibit the process of transcription then a a regulatory substance points to the regulatory protein and initiates the process of transcription. Due to the loss in the the function of the promoter gene. The process of transcription is not regulated and there is continuous process of transcription result in production of high amount of RNA from DNA by transcription and this leads to overexpression of a particular protein .The diagram shows the the structure of a promoter gene along with the coding sequence , start and stop codon .

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Please Hit the thumbs up ??Page No. Date STOP Transcription Steret site! ITSS RNA Polymerase Transcription stop Site 1 Coding Sequence Stop Codon Start

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