A gene mutation that is hypermorphic in nature likely has a mutation in its....
Promoter |
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Coding sequence |
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Intron |
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5'UTR |
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3'-UTR |
Promoter is the right option.
Because promoter is the sequence in DNA which allows RNA polymerase to bind to the transcription unit. And if there is mutation occurs in the promoter region, then it allows more binding of RNA polymerase to it. Or the promoter becomes constitutive. And there will be continuous expression of gene. RNA undergoes the process of translation and leads to protein synthesis. More the protein synthesis, more will be expression occurs in the cell.
That's why when mutation is in promoter, then there will be found more expression of genes.
A gene mutation that is hypermorphic in nature likely has a mutation in its.... Promoter Coding...
The human protein coding gene frt has three exons. A mutation at the splice junction between the second exon and first intron leads to an inability to remove a DNA segment during splicing. Which of the following is describes the most likely outcome(s) of this mutation: termination of translation within the coding sequence of the second exon termination of transcription within the coding sequence of the second intron termination of transcription before the coding sequence of the second exon termination...
The human protein coding gene frt has three exons. A mutation at the splice junction between the second exon and first intron leads to an inability to remove a DNA segment during splicing. Which of the following is describes the most likely outcome(s) of this mutation: O termination of transcription within the coding sequence of the second intron O termination of transcription before the coding sequence of the second exon termination of translation within the coding sequence of the second...
(Molecular Biology) Draw a diagram of a gene region in DNA from the promoter to end of the 3' UTR. Label the TATA box and BRE, the transcription start site, translation start site, 5' UTR, any at least two exons and 1 intron, 3' UTR, and start and stop codons.
B. (10pts) Gene expression can be regulated in many ways. In the gene below, each letter represents a different mutation. Indicate which mutation would: (Use each letter only once.) trigger non-sense mediated decay increase transcript stability result in aberrant splicing reduce mRNA expression levels alter ADAR RNA editing promoter D — transcribed region intron A intron E exon- transcription factor binding sites exon spliced mRNA T 5'UTR CDS 3'UTR start codon stop codon C. (8pts) UAU encodes the amino acid...
Which type of mutation is likely to be more harmful? Substitution O Frameshift O Silent mutation Missense Point mutation What is the coding portion of a gene called? O Exon O Transcript Intron mRNA Okasaki fragment
A mutation occurs that causes the promoter of a gene to over-express a protein. Would this most likely be a gain of function or loss of function mutation? Why?
A mutation that reduces the level of gene expression by 30% in a diploid, eukaryotic cell, without affecting the function of the produced proteins, likely occurred in which region? Stop codon of the coding region enhancer Start codon of the coding region promoter TATA-box
Genetics Worksheet Week 3: Gene Regulation and Epigenetics 1. Duchenne muscular dystrophy is caused by a mutation in a gene that is 2.5 million nucleotides in length and encodes a protein called dystrophin. The dystrophin protein itself is 3684 amino acids in length. Calculate below the approximate size of the mRNA that encodes dystrophin. Approximately what percentage of the gene that encodes dystrophin is intron sequence? The human genome encodes a much greater variety and number of proteins than the...
One allele of the APOE gene is associated with early Alzheimer’s disease, while another allele appears to help prevent Alzheimer’s. In a brain cell of an individual with the first type of allele, we find high levels of the protein. In the brain cell of an individual with the second allele, we find no protein. This indicates the mutation may be found in: A. an intron in the gene B. the stop codon C. the 3' UTR D. the promoter...
Below is the coding DNA sequence for a gene called tribble, including the wild-type and several mutant alleles. For each mutant allele, fully classify the mutation and its effect in the amino acid sequence. Wild-type 5'-ATGGCAACTACATATAGCACAGTTTGAACC-3' a. Mutant allele #1 5'-ATGGCAACTACATAAAGCACAGTTTGAACC-3' b. Mutant allele #2 5'-ATGGCAACTACATATAGCATAGTTTGAACC-3' c. Mutant allele #3 5'-ATGGCAACTACATACAGCACAGTTTGAACC-3' d. Which mutant allele is most likely to be a knockout and why?