Question

Describe what a DNA profile is and how STRs and other polymorphic fragments can be used to display the unique qualities of DNA.

Answer 1

DNA profiling is a technique in which the resemblance of any DNA with a particular DNA can be found out. Even though uniqueness is the trademark of every individual percentage of resemblance, parentage and also this technique is adopted inorder to find out the criminal from samples of the suspected person.

STR's - short tandem repeat

It is a type of molecular biology method used to compare allele twists at regular loci in DNA between two or more samples.

Since all I dividuals have polymorphism carries multiples all individuals are unique when it comes to to DNA. And similarities in DNA is only to some extent and that too in hereditary conditions.

And in STR's there is no need of trimming the DNA like in case of RFLPA which was used in early days . But now a days PCR (polymerase chain reaction) is used. In this DNA with high polymorphic regions they are repeated to form long repeated short sequence of DNA. Thus unrelated individuals have different number is repeated units thus their individuality can be preserved. Thus all individuals can be found out using DNA with least error.