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Question 18 Which of the following will most likely be observed if the spliceosome were to be inactivated? A decrease in the

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Ans- A decrease in 2' to 5' phosphodiester bond.

A spliceosome is a complex of protein involved in spilicing i.e removing introns from pre-mRNA to form mature RNA. 2' to 5' phosphodiester bond is formed to remove intron. Therefore, if spliceosome is inactivated, no splicing will occur and this bond will not be formed.

RNA lariats and RNA by alternate splicing are also produced by spliceosome therefore, by its inactivation its number will also decrease and not increase. Also, 7mGppp is cap at mRNA 5'end, spliceosome has no role related to it. Therefore, it will be unaffected by it. Hence, statement 2,3 and 4 are incorrect.

Due to time constraints only this question be done, please post rest questions seperately, THANK YOU and HAPPY TO HELP YOU!!!!

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