Holiday junction (HJ) is a very important mechanism for natural DNA recombination. HJ catalyzes DNA recombination between _________ using a special protein complex.
Select one:
a. two dsDNA
b. one dsDNA and one ssDNA
c. two ssDNA
d. All of these
e. None of these
Holiday junction (HJ) is a very important mechanism for natural DNA recombination. HJ catalyzes DNA recombination between _________ using a special protein complex.
Answer- two dsDNA
During genetic recombination, the formation of X shaped structure for the exchange of genetic material is called Holiday junction. The two dsDNA molecules form an X shaped structure and become four strands.
Genetic recombination can be defined as the recombination of DNA. This can be of two types- Homologous and site-specific recombination.
In Homologous recombination, the genetic exchange takes place between homologous chromosomes or DNA sequences. It is also called general recombination. This recombination is involved in meiotic cross over in eukaryotes and also in integration of acquired DNA in prokaryotes by transduction, conjugation and transformation.
Robin Holliday in 1964 gave the scheme of homologous recombination. This model gave the explanation of recombination between two homologous DNA molecules. Formation of heteroduplex occurs and their is an exchange of polynucleotides segment between the two homologous molecules.
For the formation of Holliday junction, two homogous DNA pairs and endonuclease makes a nick on two strands of DNA.
The DNA strands are displaced and later ligated. Once they are ligated we get a heteroduplex called Holliday junction.
Holiday junction (HJ) is a very important mechanism for natural DNA recombination. HJ catalyzes DNA recombination...
Which protein(s) is(are) involved in the Chi sequence-specific production of ssDNA from dsDNA and its recombination into other dsDNA or ssDNA? Select one: a. Rho b. RecABCD c. RuvABC d. NusA e. None of these
29. Which protein(s) is(are) involved in the Chi sequence-specific production of ssDNA from dsDNA and its recombination into other dsDNA or ssDNA? Select one: a. Rho b. RecABCD c. RUVABC d. NusA e. None of these
Which is incorrect descriptions of the genetic event initiated by the HIV reverse transcriptase (RT) upon the HIV infection? Select one: a. RT catalyzes initial synthesis of ssDNA using viral genomic RNA as the template. b. The first RNA template is degraded after ssDNA synthesis. c. The whole process is completed after synthesis of dsDNA. d. tRNAs are adopted as the first primers. e. None of these
28. Which is incorrect descriptions of the genetic event initiated by the HIV reverse transcriptase (RT) upon the HIV infection? Select one: a. RT catalyzes initial synthesis of ssDNA using viral genomic RNA as the template. b. The first RNA template is degraded after ssDNA synthesis. c. The whole process is completed after synthesis of dsDNA. d. tRNAs are adopted as the first primers. e. None of these
Which statement is correct about DNA mutation and DNA repair? A. DNA mutation always leads to an impaired protein function A Question Progress A B. All organisms have elaborate mechanisms to repair DNA damage C. DNA mutation is a temporary change in DNA sequence D. Environmental mutagens are safe and won't cause cancer E. Homologous recombination is a type of genetic recombination in which nucleotide sequences are exchanged between two totally different molecules of DNA Reset Selection
Human chromosomes are linear dsDNA and they often show topological constraints, particularly during DNA replication and transcription. Why do the chromosomal DNA would have topological constraints? A. Multitudes of H bonding between bases make long dsDNA quite stable B. Protein-DNA interactions may cause changes in the DNA topology C. Chromosomes circularize during replication and transcription D. Because of two of these options E. Because all of these options
1. The clamp loader loads the sliding clamp onto the DNA. Review the steps listed below. Which step would come SECOND? a) ATP binds to the y (gamma) subunits, which undergo a conformation change. b) Double-stranded DNA passes through the ß clamp. c) They (gamma) — p clamp —ATP complex binds primed DNA. d) Y (gamma) subunits bind to and open the clamp. e) Single-stranded DNA passes through the side of the ß clamp loader gap. 2. Which of the...
What is/are the most important factor(s) generating genetic diversity among individuals in a population of eukaryotes? a) mutation O b) independent assortment O c) genetic recombination d) b and conly e) all of the above are important in generating diversity in eukaryotes Question 8 1 pts Which of the following statements about genetic recombination is FALSE? O genetic recombination acts independently of independent assortment O genetic recombination occurs during the production of sperm O genetic recombination is important to the...
In eukaryotes, genomic DNA is wrapped around the histone complex to make chromatin. The direct contacts between DNA and the histone beads interfere bindings of the transcriptional factor proteins to their cognate sequence elements, decreasing gene activities. To increase transcriptional activity of the affected genes, the RSC/CRC complex remodels chromatins such that the ________ sequences can be amenable to formation of the transcriptional initiation complex. Select one: a. TBP-binding and TAP-binding b. Shine-Dalgarno c. start codons d. All of these...
the presence of cells in the 105C|| 40. Polypeptides, DNA and RNA are important in the process of Chemical Evolution. The properties that they share are: a) They are long, complex polymers, b) They have groups with shapes and charges that hang off the chain c) They each have the ability to interact with (bind to other molecules because of their attached groups (With shapes with charge profiles), D) All are correct. E) None are true. Thow let molerules nass...