Homework Answers
The component of the growth factor signaling is stuck in the on position and not in the off position due to the mutation. This on position renders the protein always active and allows for constant cell growth which is proliferative. Hence the given statement is FALSE.
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One event that contributes to the conversion of a normal cell into a cancerous cell is...
You have isolated an epithelial cell line which is unresponsive to EGF (normal epithelial derived cell...
You have isolated an epithelial cell line which is unresponsive to EGF (normal epithelial derived cell lines require EGF in the culture media for growth). You suspect that EGF receptor signaling in this cell line is impaired, and you designate this a mutant cell line. As an assay for EGFR signaling, you have stably transfected this mutant cell line and a normal cell line with a luciferase-based reporter construct that is responsive to the transcription factor Elk-1. You want to...
Pls give short answers. Thank you Q5 EGF pathway 23 Points A EGF EGFR GRB2 SOS...
Pls give short answers. Thank you
Q5 EGF pathway 23 Points A EGF EGFR GRB2 SOS KRAS Active RAS KRAS GOP GDP GTP RAF РІЗК MEK АКТ) ERK Growth and Suppression Proliferation of Apoptosis Shown is the EGF signaling pathway. This is a pathway that normally promotes growth during development, and inhibits apoptosis (or programmed cell death). This pathway is also involved in cancer. Epidermal growth factor (EGF) binds to its receptor (EGFR). This binding activates the protein KRAS, which...
Please answer 2-5 2. Consider a gene with a particular function. Mutation X and mutation Y...
Please answer 2-5
2. Consider a gene with a particular function. Mutation X and mutation Y cach cause defects in the function of the encoded protein, yet a gene containing both mutations X and Y encodes a protein that works even better than the original protein. The odds are exceedingly small that a single mutational event will generate both mutations X and Y. Explain a simple way that an organism with a mutant gene containing both mutations X and Y...
Please help with answers to these questions answer the ones that are straightforward like this one...
Please help with answers to these questions
answer the ones that are straightforward like this one
Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...
Do expect the cell to produce more ATP from one glucose molecule or from one fatty...
Do expect the cell to produce more ATP from one glucose molecule or from one fatty acid molecule? Explain your answer. Indicate whether the following statements are true or false. If a statement is false, explain why it is false The proteins of the electron-transport chain remove a pair of high-energy electrons from the cofactors, NADH and FADH_2, after which the electrons move across the inner mitochondrial membrane to maintain the voltage gradient. Gluconeogenesis is a linear reaction pathway that...
Data List 1. Neural Growth Factor (NGF) is a secreted protein 2. P-STAT has a DNA...
Data List 1. Neural Growth Factor (NGF) is a secreted protein 2. P-STAT has a DNA binding site 3. Erk lives in the cytosol 4. P-Erk lives in the nucleus 5. Ras (which is a completely different protein than Ras-GEF) is a GTPase switch so on with GTP and off with GDP 6. Ras-GDP is located at the plasma membrane 7. TrkA has an amino acid that can have a phosphate group added to it (a phosphorylation site) 8. TrkA...
es and that they 7) Suppose that one human rypote has the normal number of DNA...
es and that they 7) Suppose that one human rypote has the normal number of DNA proofreading and repair enzymes and that the function correctly, while another, for some reason, has no such functioning enzymes. As growth and developmen. proceeded, what differences in DNA structure in the cells and overall organism functioning would you expect to f... between the two? 8) In what normal human cells does telomerase function? In what disease does telomerase function in the cells (much to...
explain 1 or 2 molecular details in how epigenetics may allow melanoma cells to outsmart BRAF inhibitors **This is for a genetics course Seope: This science commentary claims that epigeneties pl...
explain 1 or 2 molecular details in how epigenetics may allow
melanoma cells to outsmart BRAF inhibitors
**This is for a genetics course
Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
need some assistance with this. thank you very much 1. Free radicals are __________ . (A)...
need some assistance with this. thank you very much 1. Free radicals are __________ . (A) molecules that have lost an electron (C) molecules with extra neutrons (B) escaped political prisoners (D) produced by vitamins 2. The chromosomal location of the APC gene was originally identified by finding a region of the genome that was _________ in patients with colorectal cancer. (A) deleted (B) rearranged (C) normal (D) unclear 3. The National Health Service of the United Kingdom (Britain) has...
need some assistance with this please. thank you very much 1. Free radicals are __________ ....
need some assistance with this please. thank you very much 1. Free radicals are __________ . (A) molecules that have lost an electron (C) molecules with extra neutrons (B) escaped political prisoners (D) produced by vitamins 2. The chromosomal location of the APC gene was originally identified by finding a region of the genome that was _________ in patients with colorectal cancer. (A) deleted (B) rearranged (C) normal (D) unclear 3. The National Health Service of the United Kingdom (Britain)...
Pls give short answers. Thank you
Q5 EGF pathway 23 Points A EGF EGFR GRB2 SOS KRAS Active RAS KRAS GOP GDP GTP RAF РІЗК MEK АКТ) ERK Growth and Suppression Proliferation of Apoptosis Shown is the EGF signaling pathway. This is a pathway that normally promotes growth during development, and inhibits apoptosis (or programmed cell death). This pathway is also involved in cancer. Epidermal growth factor (EGF) binds to its receptor (EGFR). This binding activates the protein KRAS, which...
Please answer 2-5
2. Consider a gene with a particular function. Mutation X and mutation Y cach cause defects in the function of the encoded protein, yet a gene containing both mutations X and Y encodes a protein that works even better than the original protein. The odds are exceedingly small that a single mutational event will generate both mutations X and Y. Explain a simple way that an organism with a mutant gene containing both mutations X and Y...
Please help with answers to these questions
answer the ones that are straightforward like this one
Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...
Do expect the cell to produce more ATP from one glucose molecule or from one fatty acid molecule? Explain your answer. Indicate whether the following statements are true or false. If a statement is false, explain why it is false The proteins of the electron-transport chain remove a pair of high-energy electrons from the cofactors, NADH and FADH_2, after which the electrons move across the inner mitochondrial membrane to maintain the voltage gradient. Gluconeogenesis is a linear reaction pathway that...
Data List 1. Neural Growth Factor (NGF) is a secreted protein 2. P-STAT has a DNA binding site 3. Erk lives in the cytosol 4. P-Erk lives in the nucleus 5. Ras (which is a completely different protein than Ras-GEF) is a GTPase switch so on with GTP and off with GDP 6. Ras-GDP is located at the plasma membrane 7. TrkA has an amino acid that can have a phosphate group added to it (a phosphorylation site) 8. TrkA...
es and that they 7) Suppose that one human rypote has the normal number of DNA proofreading and repair enzymes and that the function correctly, while another, for some reason, has no such functioning enzymes. As growth and developmen. proceeded, what differences in DNA structure in the cells and overall organism functioning would you expect to f... between the two? 8) In what normal human cells does telomerase function? In what disease does telomerase function in the cells (much to...
explain 1 or 2 molecular details in how epigenetics may allow
melanoma cells to outsmart BRAF inhibitors
**This is for a genetics course
Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
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