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Imagine an individual is suffering from low blood glucose levels and glucose can be clinically administered....

Imagine an individual is suffering from low blood glucose levels and glucose can be clinically administered. If we can intravenously supply glucose-6-phosphate to muscle cells instead of glucose, knowing that there is a cost associated with converting glucose to glucose-6-phosphate (1 ATP spend), would it be best to administer glucose-6-phosphate directly, instead of glucose to a patient in need? Would this be effective? Explain why or why not. Note: this patient is suffering from general (i.e. total body) low blood glucose levels.

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Answer #1

Yes glucose 6 phosphate can be given instead of glucose when the patient suffers low blood glucose. Glucose becomes glucose 6 phosphate and enters into glycogen or other metabolism and the conversion requires utilisation of ATP molecule and providing direct glucose 6 phosphate.

Glucose 6 phosphate isis high energy compound releases more free energy in metabolism than plain glucose . Hence glucose 6 phosphate can be utilised for intraveous administration

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