Question

Matching the normal function to the enzyme. This enzyme connects Okazaki fragments by forming bonds in the A. DNA backbone. Topoisomerase This enzyme opens the DNA helix, separating the strands to expose B. the bases. Primase This enzyme relaxes supercoils in the DNA that form ahead of the replication fork Helicase DNA Polymerase III This enzyme removes primers by cutting out one RNA nucleotide at a D. time and replacing it with DNA. DNA Polymerase This enzyme uses its own RNA template to extend the ends of E chromosomes at the end of DNA replication, preventing chromosomes from getting shorter over time. Telomerase Ligase This enzyme builds the new DNA strands by adding complementary F. nucleotides across from the template (original) strand, G. This enzyme uses RNA to get new strands started.

Answer 1

Topoisomerase - C. This enzyme relaxes supercoils in the DNA that form ahead of the replication fork.

Primase - G. This enzyme uses RNA to get new strands started.

Helicase - B. This enzyme opens DNA helix, seperating the strands to to expose the bases.

DNA polymerase III - F. This enzyme buits new DNA strands by adding complementary nucleotides across from the template ( original ) strand.

DNA Polymerase I - D. This enzyme removes primers by cutting out one RNA nucleotide at a time and replacing it with DNA .

Telomerase - E. This enzymes uses its own RNA template to extend the ends of chromosomes at the end of DNA replication, preventing chromosomes from getting shorter over time.

Ligase - A. This enzyme connects okazaki fragments by forming bonds in the DNA backbone.

Explanation-

Topoisomerase

Topoisomerase is an enzyme related to overwinding /underwinding of DNA.The enzyme was discovered by James Wang. Controls the supercoiling of DNA . Mainly 2 types

* Type 1

* Type II

Primase

Primase is a type of RNA polymerase. It produces short RNA primers during replication in 5' to 3' direction. This enzyme is active only in presence of other proteins.

Helicase

Helicase is an enzyme which unwinds DNA. They are of 2 types,

* DNA helicases

* RNA helicases

During replication, helicases seperates double stranded DNA.

DNA polymerase III

Primary enzyne involved in replication. Have 10 different polypeptides. It have

* 5' to 3' exonuclease activity

* 5' to 3' polymerase activity

* 3' to 5' proofreading

DNA polymerase I

It removes RNA primers and fill with DNA, The enzyme is composed of single polypeptide.

Telomerase

Telomerase is an enzyme which regulate the length of telomeres. It is also called Terminal transferase.

Ligase

It is a molecular glue. It joins two strands of DNA by forming bonds.