which antimicrobials would be most effective against Vibrio cholerae
as well as which would be least effective. and what mechanisms of action for the antimicrobials
Answer:
Cholera is a water-borne enteric disease characterized by rice-water stools and vomiting. It is a severe disease and if left untreated can be fatal. The severity of disease depends on the dose of Vibrio cholerae ingested.
The treatment involves, first and
foremost, rehydration of the patient with appropriate ORS as large
amounts of water and electrolytes are lost in the bouts of diarrhea
and vomiting.
The best antimicrobial effective against cholera
is doxycycline (derived from tetracycline) for
adults. For children macrolides like Erythromycin or
Azithromycin work better. Even single doses of these
antimicrobials given, show immediate effect against Vibrio
cholerae.
The least effective antimicrobial agent would be
Penicillin which is only effective against
gram-positive bacteria. Vibrio cholerae is a gram-negative comma
shaped bacteria.
which antimicrobials would be most effective against Vibrio cholerae as well as which would be least...
what antimicrobials would be most effective against proteus mirabilis and what would be least effective?
Which of the following bacteria undergo lactose fermentation? Select one: a. Campylobacter jejuni b. Vibrio Cholerae c. Bordetella pertussis d. Klebsiella
You are aware of a Vibrio cholerae operon that contains a FadL and a lipase in the same operon. Did you identify a similar operon in V. harveyi? To investigate conserved hypothetical proteins you must use NCBI and look up the protein. Then click on ‘Identify Conserved Domains.’ Describe the types of proteins that are in this V. harveyi operon. Perform an alignment between your identified lipase in V. harveyi and VCA0863 from V. cholerae N16961. Download the alignment file,...
13. Natural infection with Vibrio cholerae results in the development of long-lived protective immunity: a. What is the basis of immunity (include the protective antigen in your answer)? (2 points) b. Provide an explanation why a live vaccine strain that lacks Toxin Co-regulated pili (TCP) does not provide effective immunity. (2 points) Name: c. A live vaccine strain lacking cholera toxin A-subunit still causes mild diarrhea. Provide an explanation and how you would use this information to construct a live,...
1. Of these cellular targets of antimicrobials, drugs designed against which target are likely to have the least selective toxicity? Ribosomes Cell membrane O Cell wall Nucleic acid synthesis 2. Which of these antimicrobials has the broadest spectrum of activity? Cephalosporin Polymyxitn Tetracycline 3. Your microbilome is most susceptible to changes when takinga s spectrum antimicrobial O selective O narrovw broad . Which microbial group is the easiest to selectively target with antimicrobials? Bacteria Viruses Fung Helminths 5. Based on...
1. What type of infection is herd immunity most effective against? Least effective against? Provide an example of each. 2. How do the physical barriers (skin, mucous membranes, lungs, GI tract) prevent infection? What are chemical barriers to infection?
return 87. What growth plating medium would selectively isolate Vibrio cholerae from an infected patient TCES 0OO 88. What would be and staining reaction/morphology/grouping 89. The main symptom(s)ior 90. Timing (hrs or days in blank) of appearance of symptoms if positive and consumed 2 hiS? dbess and Enteric plating media (e.g., MacConkey and EMB agars) have which sugar and a pH indicator to distinguish coliforms from non coliforms? Glucose ucrose Lactose Maltose Answer to question above (pick one from A-E...
Why is Streptomycin only effective against bacteria, and not archaea as well? I thought its mechanism of action had to do with its binding site on the 30S ribosomal subunit, but archaea have this as well, so why is it not effective against both? For reference, I was asked to explain how the mode of action of each antibiotic relates to the organisms in each domain. is down partenere a cyclo acteria on the basis of sensitivity to antimicrobial chemicals....
Which antibiotic(s) is/are the most effective? Which antibiotic(s) is/are the least effective? The bacteria used was E.coli and the antibiotics are shown in the diagram on the right. Results gentamycin penicillin Tetra polymixin Nalidixid cycline acid PAN SA Sulfa drug (sulfonamide)
What have been the most effective efforts against drug cartels?