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what antimicrobials would be most effective against proteus mirabilis and what would be least effective?

what antimicrobials would be most effective against proteus mirabilis and what would be least effective?

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Ans) Proteus mirabilis is a gram negative bacteria .Most effective treatment is from Cephalosporin, Basically it become resistant to various antibiotics .So, the used antibotics are aminoglycosides, carbapenems (except imipenem), and 3rd generation cephalosporins as they disrupt the synthesis of the peptidoglycan layer forming the bacterial cell wall.Least effective may be ampicillin and First generation cephalosporin as they have developed resistant towards it and this antibiotic inhibits the cell wall synthesis so it doesnot disrupt it as develop resistant towards it.

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