Homework Answers
ANSWER ) MYOSIN LIGHT CHAIN KINASE
EXPLANATION
MYOSIN LIGHT CHAIN KINASE (MLCK) IS A SERINE/ THEORINE KINASE WHICH IS DEPENDENT ON CALMODULIN FOR ITS ACTIVATION. ONCE THE INTRACELLULAR CALCIUM CONCENTRATION INCREASES IT LEAD TO ACTIVATION OF THE CALMODULIN. MLCK CONSIST OF THREE DOMAIN WHICH INCLUDES ACTIN BINDING DOMAIN ( PRESENT ON N- TERMINAL), MYOSIN BINDING DOMAIN AND CALMODULIN BINDING DOMAIN ( BOTH PRESENT ON C TERMINAL)
ONCE CALMODULIN BIND TO THE DOMAIN OF MLCK LEADS TO ITS ACTIVATION THUS FURTHER PHOSPHORYLATE AT SERINE AND THREONINE AT 19 AND 18 POSITION OF MYOSIN LIGHT CHAIN. THIS PHOSPHORYLATION INCREASE THE CROSSBRIDGING BETWEEN ACTIN AND MYOSIN RESULTING IN CONTRACTION OF THE MUSCLE.
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QUESTION 7 What happens (immediately) if T-tubules blocked in skeletal muscle action potential increased an action potential blocked from progressing in fibril Myosin phosphatase in muscle O4(MP) activated d. inactivated QUESTION 8 Can be activated by stretch receptors (best answer only) a. Skeletal muscle Ob. smooth muscle Oc. myosin light chain phosphataso Od. A and B QUESTION 9 Action potential leads to activation of neurotransmitter in muscle answer true or false a true b. false c. not sure od silly...
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please help..
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