Homework Answers
1. Answer - B
Nucleosome is the basic unit of chromosome. It consists of a double helix up to 147 base pairs around the octane of histone proteins. There are two set of histones - H2A, H2B , H3 and H4.
2. Answer - B
Histone H1 plays an important role in the stabilizing of chromatin fibre by binding with 20-80 base pairs long "linker DNA".
3. Answer - A
Euchromatin participates in active transcription so a mRNA is formed from DNA.
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QUESTION 1 A nucleosome consists of A. a cluster of histone proteins that are wrapped around...
1. In assembling a nucleosome, normally the …(1) histone dimers first combine to form a tetramer,...
1. In assembling a nucleosome, normally the …(1) histone dimers first combine to form a tetramer, which then further combines with two … (2) histone dimers to form the octamer. A. 1: H1–H3; 2: H2A–H2B B. 1: H3–H4; 2: H2A–H2B C. 1: H2A–H2B; 2: H1–H3 D. 1: H2A–H2B; 2: H3–H4 E. 1: H1–H2; 2: H3–H4 2. There has been a mutation on several enzymes important in DNA replication. For each enzyme, discuss what the protein normally does and how the...
Abstract #1 Histone H3 phosphorylation near the nucleosome dyad alters chromatin structure. Nucleosomes contain ∼146 bp...
Abstract #1 Histone H3 phosphorylation near the nucleosome dyad alters chromatin structure. Nucleosomes contain ∼146 bp of DNA wrapped around a histone protein octamer that controls DNA accessibility to transcription and repair complexes. Posttranslational modification (PTM) of histone proteins regulates nucleosome function. To date, only modest changes in nucleosome structure have been directly attributed to histone PTMs. Histone residue H3(T118) is located near the nucleosome dyad and can be phosphorylated. This PTM destabilizes nucleosomes and is implicated in the regulation...
Question: A diploid nucleus of Drosophila melanogaster contains about 3.4 x 108 nucleotide pairs. Assume (1)...
Question: A diploid nucleus of Drosophila melanogaster contains about 3.4 x 108 nucleotide pairs. Assume (1) that all nuclear DNA is packaged in nucleosomes and (2) that an average internucleosome linker size is 60 nucleotide pairs. How many nucleosomes would be present in a diploid nucleus of D. melanogaster? How many molecules of histone H2a, H2b, H3, and H4 would be required? ANS: In the diploid nucleus of D. melanogaster, 1.65 x 106 nucleosomes would be present; these would contain 3.3...
3. Persistence length of DNA and energy cost of bending DNA around histone proteins (a) DNA is st...
3. Persistence length of DNA and energy cost of bending DNA around histone proteins (a) DNA is stiff because it is a double helix. At room temperature in dilute solution the persistence length of DNA is found to be p-50 nm. Using this persistence length, find the bending spring constant of DNA (b) In chromosomes, DNA molecules are wrapped tightly around histones. Consider wrapping a DNA molecule around a full circle, estimate the energy cost of bending DNA around the...
thank you!! Question 1 0.5 pts It has been shown that inhibition of a key chromatin...
thank you!!
Question 1 0.5 pts It has been shown that inhibition of a key chromatin remodeling complex known as NURD. by deleting one of its subunits, can result in a significant increase in the efficiency of reprogramming of somatic cells into pluripotent stem cells. The reprogramming is normally done by the induced expression of a battery of transcription factors in the somatic cells, but is typically not very efficient. Such an observation suggests that the NURD complex is normally...
1. DNA is coiled around what type of proteins to form nucleosomes A. Polymerases DNA replication...
1. DNA is coiled around what type of proteins to form nucleosomes A. Polymerases DNA replication of the lagging strand is discontinuous B. Transcription factors DNA replication of the lagging strand is continuous C. Helicases D. Histones E. DICER 2. Which of the following statements is true? A. DNA replication of the leading strand is discontinuous B. DNA replication of the lagging strand is discontinuous C. DNA replication of the leading strand is dispersive D. DNA replication of the lagging...
please answer all the questions Question 8 0 / 1 pts Our understanding of RNA ...
please answer all the questions
Question 8
0 / 1 pts
Our understanding of RNA
was non-existent until 2000
started with the identification of a tRNA which suggested a
method of converting DNA to protein
began to identify that DNA-->protein--> RNA
stopped growing after it's original discovery in the 70s
IncorrectQuestion 10
0 / 1 pts
Enzymes allow for chemical reactions to occur in the cell that
may not naturally occur at the right place at...
1. the genes that seem to be the most necessary to maintain, since they are present...
1. the genes that seem to be the most necessary to maintain, since they are present in the smallest cellular organisms are a. cytoskeletal protein genes b, translation protein genes c. replication protein genes d. transcription protein genes e. DNA repair protein genes 2. Why do cellular organisms generally look very similar when early embryos but different from each other when mature? a. their DNAs have different chemistry b. their RNAs are different lengths c. what genes get turned on...
please answer All the multiple choice questions in the pic (all pics) i dont need a...
please answer All the multiple choice questions in the pic (all
pics) i dont need a explantion .
22 Using a bacteriophage to pass DNA rom bacterium to another O A) Transduction O B) Transformation C) Translocation O D) Translation 23. What research did Rosalind Franklin contribute to the elucidation of the double helix structure of DNA? O O O A) Principles of base pairing B) Biochemical data C) Bacterial transformation data D) X ray crystallography A segment of DNA...
3. Persistence length of DNA and energy cost of bending DNA around histone proteins (a) DNA is stiff because it is a double helix. At room temperature in dilute solution the persistence length of DNA is found to be p-50 nm. Using this persistence length, find the bending spring constant of DNA (b) In chromosomes, DNA molecules are wrapped tightly around histones. Consider wrapping a DNA molecule around a full circle, estimate the energy cost of bending DNA around the...
thank you!!
Question 1 0.5 pts It has been shown that inhibition of a key chromatin remodeling complex known as NURD. by deleting one of its subunits, can result in a significant increase in the efficiency of reprogramming of somatic cells into pluripotent stem cells. The reprogramming is normally done by the induced expression of a battery of transcription factors in the somatic cells, but is typically not very efficient. Such an observation suggests that the NURD complex is normally...
1. DNA is coiled around what type of proteins to form nucleosomes A. Polymerases DNA replication of the lagging strand is discontinuous B. Transcription factors DNA replication of the lagging strand is continuous C. Helicases D. Histones E. DICER 2. Which of the following statements is true? A. DNA replication of the leading strand is discontinuous B. DNA replication of the lagging strand is discontinuous C. DNA replication of the leading strand is dispersive D. DNA replication of the lagging...
please answer all the questions
Question 8
0 / 1 pts
Our understanding of RNA
was non-existent until 2000
started with the identification of a tRNA which suggested a
method of converting DNA to protein
began to identify that DNA-->protein--> RNA
stopped growing after it's original discovery in the 70s
IncorrectQuestion 10
0 / 1 pts
Enzymes allow for chemical reactions to occur in the cell that
may not naturally occur at the right place at...
please answer All the multiple choice questions in the pic (all
pics) i dont need a explantion .
22 Using a bacteriophage to pass DNA rom bacterium to another O A) Transduction O B) Transformation C) Translocation O D) Translation 23. What research did Rosalind Franklin contribute to the elucidation of the double helix structure of DNA? O O O A) Principles of base pairing B) Biochemical data C) Bacterial transformation data D) X ray crystallography A segment of DNA...
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