Homework Answers
BRCA2 gene is located on the chromosome 13,another DNA repair gene,in its mutated form,has a similarity higher incidence of inherited cancer of breast in one third cases and ovary in females and prostate in men.
In BRCA1 as well as BRCA2 ,both copies of the genes[homozygous state] must be inactivated for the development of breast cancer.
Most BRCA2 gene mutations lead to the production of an abnormally small, nonfunctional version of the BRCA2 protein from one copy of the gene in each cell. As a result, less of this protein is available to help repair damaged DNA or fix mutations that occur in other genes.
Add Answer to:
Please explain in details
Using the ActiveModel for Brca2 (the protein encoded by the BRCA2 gene...
IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS OUTCOME 5. a), Why are Proto-Oncogenes important for...
IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS
OUTCOME
5. a), Why are Proto-Oncogenes important for the cell cycle control and what is their implication in a progression of tumors and cancers? Provide examples of TWO proto-oncogenes and a type of a cancer each is associated with. (6 pts) b) Now consider the diagram below. Under each of three scenarios, explain a likely cellular consequence relative to gene expression and protein synthesis outcome, assuming each could lead to a development...
Please answer 2-5 2. Consider a gene with a particular function. Mutation X and mutation Y...
Please answer 2-5
2. Consider a gene with a particular function. Mutation X and mutation Y cach cause defects in the function of the encoded protein, yet a gene containing both mutations X and Y encodes a protein that works even better than the original protein. The odds are exceedingly small that a single mutational event will generate both mutations X and Y. Explain a simple way that an organism with a mutant gene containing both mutations X and Y...
An enzyme, encoded by gene A, converts substrate X into product Y. Individuals with a dominant...
An enzyme, encoded by gene A, converts substrate X into product Y. Individuals with a dominant mutation in gene A over accumulate substrate X, which causes severe neurological symptoms. At the molecular level, this enzyme functions as a homodimer. A homodimer is a protein composed of two subunits that are encoded by the same gene. Let’s suppose you are able to purify subunits from cell samples and then mix them together under conditions in which they form homodimers, and you...
For Biology of Cancer- Please Explain The regulation of expression of the Ah locus, the protein...
For Biology of Cancer- Please Explain The regulation of expression of the Ah locus, the protein products regulated by the activities of each gene, the mechanisms of AH-induced gene expression. Should be able to reason (and give an example) on how a selective or aberrant regulation of the Ah-locus might affect the predisposition to malignancies associated with exposure to AH (such as in smoking).
A geneticist discovers that two different proteins are encoded by the same gene. One protein has...
A geneticist discovers that two different proteins are encoded by the same gene. One protein has 56 amino acids, and the other has 82 amino acids. Which of the statements are possible explanations for how the same gene can encode both of these proteins? 1-The same gene encodes both proteins by using different combinations of introns in the pre‑mRNA via alternative splicing. 2-The same gene encodes both proteins by generating a poly(A) tail on the pre‑mRNA. 3-The same gene encodes...
please answer all 6 questions Question 27 3 pts TRBP is a protein important for the...
please answer all 6 questions
Question 27 3 pts TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP? o Reduced siRNA-mediated mRNA degradation o Increased miRNA-mediated translational repression o Increased deadenylase-mediated mRNA degradation o Reduced proteasome-mediated protein degradation D Question 28 3 pts A protein that binds to the 3' UTR of a VEGF mRNA and promotes deadenylation and uncapping is likely to:...
I need a reply to the discussion below! Debate forum 3: Debate question, is bilateral mastectomy...
I need a reply to the discussion below! Debate forum 3: Debate question, is bilateral mastectomy a good preventative choice for women who have all the genetic markers for breast cancer? Yes is it a good choice for women who have all the genetic markers for breast cancer, but for women who don’t have all the genetic markers it is not necessarily a good choice. Breast cancer is the most common cause of cancer in women and second cause of...
Short explain and type please What is the daf-2 gene and how did a mutation to...
Short explain and type please What is the daf-2 gene and how did a mutation to this gene affect C elegans? Could a mutation to this gene affect humans the same way? Explain.
please answer all the question to get a like. Part III Dr. Hernandez sits down with...
please answer all the question to get a like. Part III Dr. Hernandez sits down with Ann and her partner. The doctor is sorry to report that Ann has breast cancer; however, because it was caught early and responds to estrogen and progesterone, the prognosis is good. At this point it looks like the cancer is stage 1. However, as Ann is young, the doctor wants to perform a couple of tests. The first test is a genetic sequencing test...
Our study uses CRIPSR targeting vectors to the ALK and ELM4 genes. What is the ALK...
Our study uses CRIPSR targeting vectors to the ALK and ELM4 genes. What is the ALK gene and normal function (include signaling pathway)? - Anaplastic lymphoma kinase is an enzyme that is encoded by the ALK gene in humans. It plays a significant role in cellular communication, normal development and function of the nervous system, and plays crucial roles in adult behavior. What type of cancer is associated with mutation of the ALK and EML4 genes? - It is associated...
IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS
OUTCOME
5. a), Why are Proto-Oncogenes important for the cell cycle control and what is their implication in a progression of tumors and cancers? Provide examples of TWO proto-oncogenes and a type of a cancer each is associated with. (6 pts) b) Now consider the diagram below. Under each of three scenarios, explain a likely cellular consequence relative to gene expression and protein synthesis outcome, assuming each could lead to a development...
Please answer 2-5
2. Consider a gene with a particular function. Mutation X and mutation Y cach cause defects in the function of the encoded protein, yet a gene containing both mutations X and Y encodes a protein that works even better than the original protein. The odds are exceedingly small that a single mutational event will generate both mutations X and Y. Explain a simple way that an organism with a mutant gene containing both mutations X and Y...
please answer all 6 questions
Question 27 3 pts TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP? o Reduced siRNA-mediated mRNA degradation o Increased miRNA-mediated translational repression o Increased deadenylase-mediated mRNA degradation o Reduced proteasome-mediated protein degradation D Question 28 3 pts A protein that binds to the 3' UTR of a VEGF mRNA and promotes deadenylation and uncapping is likely to:...
Most questions answered within 3 hours.
-
The resistance of the body varies from approximately 500 kΩ
(when it is very dry) to...
asked 10 seconds from now -
Please explain how participation income and expenses are
allocated to each partner. Where is this defined?
asked 9 minutes ago -
The tires of a car make 61 revolutions as the car reduces its
speed uniformly from...
asked 24 minutes ago -
Peabody, Inc., sells fireworks. The company’s marketing director
developed the following cost of goods sold budget...
asked 28 minutes ago -
A signal transduction pathway includes the steps listed
below.
1. An inactive signal transduction molecule is...
asked 27 minutes ago -
1. The correlation coefficient determined for two variables has
a value of 0.89. Describe, in words,...
asked 33 minutes ago -
The following data relate to direct materials costs for
November:
Actual costs
4,700 pounds at $5.35...
asked 32 minutes ago -
Kyle, a 95.0 kg football player, leaps straight up into the air
(with no horizontal velocity)...
asked 56 minutes ago -
Which of the following is a measure of profitability?
A.
Quick (acid-test) ratio
B.
Net sales...
asked 58 minutes ago -
Find the total pressure exerted by 2 grams of ethane and 3 grams
of CO2 contained...
asked 1 hour ago -
A fireman standing on a 5.2 m high ladder operates a water hose
with a round...
asked 56 minutes ago -
A cream formulation is studied for accelerated stability study.
Creaming was observed when formulation was tested...
asked 59 minutes ago