Write the products and the appropriate stepwise mechanism for the following reactions: (a) 1-bromobutane+ Nal (b)...
1. Write the overall balanced reaction equation for the following reactions: 1-bromobutane + CH3CH,OH + AgNO3 2-bromobutane + CH,CH,OH + AgNO3 2-bromo2-methylpropane + CH CH OH + AgNO3 — 2. For the solvolysis reaction of 2-bromo-2-methylpropane with ethanol in presence of silver nitrate: a. Write the balanced equation for the reaction b. Identify the substrate, nucleophile, leaving group and the solvent c. What is the role of silver nitrate d. Write the mechanism of the reaction(with arrows showing the movement...
1. Determine whether the following reactions will go through SN1, SN2, E1, or E2 mechanism a. 1-bromobutane + sodium hydroxide b. 2-chloro-2-methylpentane + sodium hydroxide + heat C. 2,3-dimethyl-3-bromopentane + water d. 2-bromobutane + methanol 2. Draw the major product for the following reactions (draw both products if racemic): NaSH DMSO TsO CHA Nal CH, acetone CH,CH,ONa+ ethanol CH,OH/H-0 Solite Nal (1 equiv.) acetone F CH2CH OH 25°C
1. Write the mechanism for the Sn2 reaction of 1-bromobutane with iodide ion. 2. Write the mechanism for the Sn1 reaction of 2-bromo-2-methylpropane with ethanol(EtOH).
(1) What mechanism do you believe will be favored with Nal in acetone? What order of reactivity do you predict will be observed when each of the alkyl halides in Figure 1 is reacted with Nal in acetone? Complete the below table; list the relative ranking of the reactivity of the alkyl halides and your reason for placing that alkyl halide at that ranking. Write your prediction of the mechanism and the order of reactivity with Nal in acetone as...
-Compare rates of S2 and SN1 product formation for 5 halides (1-chlorobutane, 1- bromobutane, 2-bromobutane, 2-chloro-2-methylpropane, and chlorobenzene) -Arrange 5 compounds in order of decreasing reactivity toward (a) Nal in acetone, and (b) AgNO3 in ethanol reagents. [Use structural formula for halides]
Predict the substitution product(s) for each of the following reactions and mechanisms by which they are formed. If no reaction is expected, write no (a) (R)-2-bromobutane with sodium iodide in acetone (b) (R)-3-bromo-3-methylhexane with H20 (c) trans-1-bromo-2-ethylcyclopentane with potassium ethoxide in ethanol (d) trans-1-bromo-3-methylcyclopentane with Nal in acetone 5. For the following set of compounds, predict the order of reactivity with sodium iodide in acetone solution (list them in increasing order of reactivity). C. D. 2-bromobutane 1-chlorobutane 2-chloro-3-methylbutane 2-bromo-2-methylpropane 1-bromobutane...
Complete the following reactions and state the dominant mechanism acetone b. (R)-2-bromobutane + Nash mechanism: c. (18,2S)-1-bromo-1,2-diphenylpropane methanol + NaOCH; mechanism: d. 3-chloro-2,2-dimethylbutane + NaSCH; mechanism: t-BuOH e. 2-chloro-2-methylpentane + (CH3),CONa H).CoNa BUCH mechanism:
Write balanced equations and draw the structure for any reactions undergone by each alkyl halide with AgNO3/ethanol 2-bromobutane, 2-bromo-2-methylpropane, 1-bromobutane, bromocyclohexane, 1-bromoadamantane and write out mechanism for the reaction of 2-bromobutane in AgNO3/Ethanol
Write balanced equations and draw the structure for any reactions undergone by each alkyl halide with Nal/Acetone: 2-bromobutane, 2-bromo-2-methylpropane, 1- bromobutane, bromocyclohexane, 1-bromoadamantane and write out mechanism for the reaction 2-bromobutane in NaO/Acetone
Name Exp. 10 Post-lab Report Organic Chemistry I Nucleophilic Substitution Reactions PART 1.Nal /acetone Alkyl halide Structure 1-bromobutane 1-chlorobutane 2-chlorobutane 2-chloro-2- methylpropane chlorobenzene benzyl chloride