The “replisome” is the complex of proteins located at a replication fork. Which of the following...
The “replisome” is the complex of proteins located at a replication fork. Which of the following is NOT required in a replisome in E. coli?
Primase.
DNA ligase.
Pol I.
DNA gyrase.
DnaA.
Homework Answers
Answer: DNA ligase
Reason: The replisome or the replicasome of the bacteria is a complex arrangement of specific protein units and enzymes which help in DNA replication at the replication bubble. The complex includes all the enzymes and proteins required for opening and stabilization of the DNA helix, but not the enzyme required for re-sealing of the helix. Since DNA ligase introduces sealing of the DNA strands, it does not make a part of the replisome.
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The “replisome” is the complex of proteins located at a
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