Question

A student is attempting to formulate a new, stronger UV-blocking sunscreen in a laboratory. The student uses a particular strain of hairless mice and applies the experimental sunscreen to the experimental group of mice. The student then runs a negative control group and a positive control group, which consist of hairless mice with no sunscreen and hairless mice with a validated sunscreen product applied, respectively. The groups of mice are then exposed to equal amounts of high-dose UV radiation. Which of the following data would indicate that the experimental sunscreen product is more effective than the validated sunscreen product?

A.) The experimental group will have higher p53 activity.

B.) The experimental group will have a more severe sunburn.

C.) The experimental group will show fewer chromosomal rearrangements.

D.) The experimental group will contain fewer CC → TT mutations in their epithelia.

Answer 1

The data would indicate that the experimental sunscreen product is more effective than the validated sunscreen product is that the experimental group will contain fewer CC → TT mutations in their epithelia. This is because, the UV light form Thymine dimers (TT Thus, the correct option is (D)