Question

2. If I drink simultaneously one shot of Bourbon (1% oz, 40% vol), one shot of scotch (1% oz, 40% vol) and one beer (12 oz, 5% vol). How long will it take to completely metabolize ethanol from my system if my mass is 100 kg? 3. From the three drinks in question no. 2, how many Calories are strictly derived from alcohol? Write out the complete metabolism of ethanol in our body. Include all enzymes involved and the location in which the reactions are taking place. 4.

Answer 1

2. According to given information if we caluculate Blood alcohol concentration BAC caluculator

BAC = [Alcohol consumed in grams / (Body weight in grams x r)] x 100. In this formula, “r” is the gender constant: r = 0.55 for females and 0.68 for males.^[1]

weight:100 kg lbs

Percent of body capable of absorbing alcohol (Usual ranges):

Time spent drinking or time elapsed.   Hours :0

Volume consumed:15 ml Fluid oz   Number of drinks:3

Alcohol units: 165 percent (ABV) proof (e.g. 50% or 100 proof) Beverage Usual Volume Usual Concentration Beer 12 or 16 oz 5.0 % Wine 2.5 or 5oz 12.0 % 1 Shot 1.25 oz 80 proof Results Blood alcohol concentration: 1406.0 mg/dl Blood alcohol level: 1.406 g/dL = 1.406 %(w/v) Time to Metabolize Alcohol= Blood Alcohol Level/20mg/dl it takes 70.3 hours of time to metabolize ethanol completely from body 3. 105 calories in a 1shot serving of Bourbon. All of thesecalories come from alcohol alone, with no calories derived from carbohydrates, fat or protein. 96 calories for 1 shot of scoth and 1 beer bottle contains 150 calories 4. Alcohol is metabolized in the body mainly by the liver. The brain, pancreas, and stomach also metabolize alcohol

Alcohol dehydrogenase Ethanol H,C-CH2-OH Acetate Hc-coo Catalase peroxisomes) Aldchyde dehydrogenase P4502E1 microsom03) Alcohol is metabolized by several processes or pathways. The most common of these pathways involves two enzymes—alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). These enzymes help break apart the alcohol molecule, making it possible to eliminate it from the body. First, ADH metabolizes alcohol to acetaldehyde, a highly toxic substance and known carcinogen . Then, in a second step, acetaldehyde is further metabolized down to another, less active byproduct called acetate , which then is broken down into water and carbon dioxide for easy elimination. The enzymes cytochrome P450 2E1 (CYP2E1) and catalase also break down alcohol to acetaldehyde. However, CYP2E1 only is active after a person has consumed large amounts of alcohol, and catalase metabolizes only a small fraction of alcohol in the body (1). Small amounts of alcohol also are removed by interacting with fatty acids to form compounds called fatty acid ethyl esters (FAEEs). These compounds have been shown to contribute to damage to the liver and pancreas acetaldehyde. Although acetaldehyde is short lived, usually existing in the body only for a brief time before it is further broken down into acetate, it has the potential to cause significant damage. This is particularly evident in the liver, where the bulk of alcohol metabolism takes place . Some alcohol metabolism also occurs in other tissues, including the pancreas and the brain, causing damage to cells and tissues . Additionally, small amounts of alcohol are metabolized to acetaldehyde in the gastrointestinal tract, exposing these tissues to acetaldehyde’s damaging effects