What would most likely happen if M-cyclin is replaced by a nondegradable M-cyclin? A : The...
What would most likely happen if M-cyclin is replaced by a nondegradable M-cyclin?
A : The cell cycle would proceed as normal
B : The cell cycle would not initiate and the cells would remain in G0.
C : Cells would complete one cell cycle but would not start the next cell cycle.
D : Cells would complete G1, S, and G2, but cannot enter the M phase.
E : Cells would enter M phase but would not exit mitosis.
Homework Answers
What would most likely happen if M-cyclin is replaced by a nondegradable M-cyclin?
Answer: E. Cells would enter M phase but would not exit mitosis.
M cyclin concentration starts increasing as the cell enters the M phase, especially during Metaphase-anaphase. Once the separation of sister chromatids takes place the M cyclin starts degrading and this causes the exit of the cell from mitosis phase and cytokinesis so when the nondegradable M-cyclin will be present, after chromosome separation it won't degrade and as a result, the cell will not exit the mitosis phase.
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What would most likely happen if M-cyclin is replaced by a
nondegradable M-cyclin?
A : The...
QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin,...
QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin, what would happen? (hint - look at slide with cell fusion experiments) The G1 cell would complete mitosis with daughter cells that have 18 chromosomes each The G1 cell would enter mitosis but arrest at the spindle checkpoint because the chromosomes were not properly replicated The G1 cell would complete mitosis with daughter cells that have 36 chromosomes each The G1 cell would go...
2. Cyclin B plus CDC2 are necessary for a checkpoint at the G2->M transition that makes...
2. Cyclin B plus CDC2 are necessary for a checkpoint at the G2->M transition that makes sure chromosomes are intact before mitosis begins. If you irradiate cells in G2 phase with gamma rays, which damages the DNA that was successfully replicated in S-phase, cells delay entry into mitosis until the DNA damage is repaired. If you inactivated that Cyclin B/ CDC2 checkpoint with the drug wortmannin and irradiated cells in G2, what would happen? a) Cells would never enter mitosis...
1.a) Suppose that a genetic alteration resulted in the synthesis of cyclin-dependent kinases that no longer...
1.a)
Suppose that a genetic alteration resulted in the synthesis of
cyclin-dependent kinases that no longer provided the "go" signal at
the cellular checkpoint. Predict the immediate outcome if this were
to alter the normal cell life-cycle processes at the G2
checkpoint. The cells involved would
A. grow and otherwise function undergoing mitosis
B. exit the cell cycle completely and enter a nondividing
cellular state
C. most likely remain in suspended metaphase, unable to enter
anaphase
D. proceed as normal,...
Question 1 2 pts A mutation in the gene for a cyclin protein might result in...
Question 1 2 pts A mutation in the gene for a cyclin protein might result in which of the following? unregulated cell cycle all of the answers a cell with less genetic material than normal none of the answers O a cell with more genetic material than normal Question 3 2 pts What would be the outcome if a cell completed mitosis but did not undergo cytokinesis? The cell would have 92 chromosomes. There would be two cells. The cell...
QUESTION 1 A gene that encodes a protein that stimulates progression of the cell cycle is...
QUESTION 1 A gene that encodes a protein that stimulates progression of the cell cycle is known as a proto-oncogene. True False QUESTION 2 Cytokinesis occurs after which stage or phase of the cell cycle? a. G2 b. S c. G0 d. G1 e. M phase QUESTION 3 During cell-cycle checkpoints, protein kinases known as CDKs phosphorylate target proteins only when they associate with a cyclin. True False QUESTION 4 During mitosis, many of the spindle fibers attach to chromosomes...
l 1. What are the two molecular functions of M-cyclin with regard to the activation of M-Cak m-cyctin 2. Fill in the blanks: The pathway that is activated in response to DNA damage in G1 involves...
l
1. What are the two molecular functions of M-cyclin with regard to the activation of M-Cak m-cyctin 2. Fill in the blanks: The pathway that is activated in response to DNA damage in G1 involves activation of which induces the complexes and inhibits them.ge,which encodes aprotein that binds to t's say a yeast temperature sensitive mutant has a mutation in the M cyclin gene which does not inactivate growth at the restrictive temperature (non-permissive temperature), resulting the M-cyclin protein...
6.) Mitogens are (b) transcription factors important for cyclin production (c) kinases that cause cells to...
6.) Mitogens are (b) transcription factors important for cyclin production (c) kinases that cause cells to grow in size (a) extracellular signals that stimulate cell division. d) produced by mitotic cells to keep nearby neighboring cells from dividing 7.) Which of the following cyclins is most active during mitosis? (a) cyclin A (b) cyclin B (c) cyclin C (d) cyclin D 8) Which molecule inactivate itotic cyclin-CDK complexes using phosphorylation? (a) Cdc25 (b) Cdc6 (c) Weel (d) Helicase 9.) What...
QUESTION 7 Quiescent cells are cells which are in Go stage of the cell cycle. What stimulus would be required for these...
QUESTION 7 Quiescent cells are cells which are in Go stage of the cell cycle. What stimulus would be required for these Go cells to re-enter the cell cycle? What event(s) occur after stimulation? Hint: Your complete response should include genes being transcribed and the different factors associated with that process ▼T·-·-▼ TTT Arial 3 (12pt) ▼ QUESTION 8 Consider that same cells in GO. In order for these cells to divide normally. they would need to renter G1 and...
QUESTION 1 Which of these proteins is responsible for preventing cell cycle progression if DNA damage...
QUESTION 1 Which of these proteins is responsible for preventing cell cycle progression if DNA damage is detected? Rb p53 ras E7 1 points QUESTION 2 Which of the following is a proto-oncogene? Cyclin Cdk ras All of the above 1 points QUESTION 3 The photograph below shows a chromosome. In what phase of the cell cycle was the cell from which this chromosome taken? G1 S G2 M Interphase 1 points QUESTION 4 Which of the...
Cells in the most adult bodis are in the restin state known as G0 phase. When...
Cells in the most adult bodis are in the restin state known as G0 phase. When can G0 phase be induced? Points: 1 Any time in the cell cycle. During G2 phase. During the mitotic phase. During the G1 phase. During S phase. The Gap 1, DNA synthesis, and Gap 2 phases of the cell cycle are collectively called Points: 1 prophase. interphase. prephase. mitosis. anaphase. Which of the following can produce an XYY individual after fertilization? Points: 1 Nondisjunction...
QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin, what would happen? (hint - look at slide with cell fusion experiments) The G1 cell would complete mitosis with daughter cells that have 18 chromosomes each The G1 cell would enter mitosis but arrest at the spindle checkpoint because the chromosomes were not properly replicated The G1 cell would complete mitosis with daughter cells that have 36 chromosomes each The G1 cell would go...
2. Cyclin B plus CDC2 are necessary for a checkpoint at the G2->M transition that makes sure chromosomes are intact before mitosis begins. If you irradiate cells in G2 phase with gamma rays, which damages the DNA that was successfully replicated in S-phase, cells delay entry into mitosis until the DNA damage is repaired. If you inactivated that Cyclin B/ CDC2 checkpoint with the drug wortmannin and irradiated cells in G2, what would happen? a) Cells would never enter mitosis...
1.a)
Suppose that a genetic alteration resulted in the synthesis of
cyclin-dependent kinases that no longer provided the "go" signal at
the cellular checkpoint. Predict the immediate outcome if this were
to alter the normal cell life-cycle processes at the G2
checkpoint. The cells involved would
A. grow and otherwise function undergoing mitosis
B. exit the cell cycle completely and enter a nondividing
cellular state
C. most likely remain in suspended metaphase, unable to enter
anaphase
D. proceed as normal,...
Question 1 2 pts A mutation in the gene for a cyclin protein might result in which of the following? unregulated cell cycle all of the answers a cell with less genetic material than normal none of the answers O a cell with more genetic material than normal Question 3 2 pts What would be the outcome if a cell completed mitosis but did not undergo cytokinesis? The cell would have 92 chromosomes. There would be two cells. The cell...
l
1. What are the two molecular functions of M-cyclin with regard to the activation of M-Cak m-cyctin 2. Fill in the blanks: The pathway that is activated in response to DNA damage in G1 involves activation of which induces the complexes and inhibits them.ge,which encodes aprotein that binds to t's say a yeast temperature sensitive mutant has a mutation in the M cyclin gene which does not inactivate growth at the restrictive temperature (non-permissive temperature), resulting the M-cyclin protein...
6.) Mitogens are (b) transcription factors important for cyclin production (c) kinases that cause cells to grow in size (a) extracellular signals that stimulate cell division. d) produced by mitotic cells to keep nearby neighboring cells from dividing 7.) Which of the following cyclins is most active during mitosis? (a) cyclin A (b) cyclin B (c) cyclin C (d) cyclin D 8) Which molecule inactivate itotic cyclin-CDK complexes using phosphorylation? (a) Cdc25 (b) Cdc6 (c) Weel (d) Helicase 9.) What...
QUESTION 7 Quiescent cells are cells which are in Go stage of the cell cycle. What stimulus would be required for these Go cells to re-enter the cell cycle? What event(s) occur after stimulation? Hint: Your complete response should include genes being transcribed and the different factors associated with that process ▼T·-·-▼ TTT Arial 3 (12pt) ▼ QUESTION 8 Consider that same cells in GO. In order for these cells to divide normally. they would need to renter G1 and...
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