Question

1. True or False: Different cells in an individual’s body have different genomes

2. Which of the following describes a genome-wide association study?

A) A study that sequenced the genome of an aggressive metastatic breast cancer biopsy from a 22-year-old patient to determine the genetic mutations present

B) A study that treated adult somatic cells with a transcription factor to understand how that transcription factor changes gene expression and the cellular phenotype

C) A California study that sequenced the CFTR gene in all newborns to determine the frequency of the recessive allele that causes cystic fibrosis

D) A study that compared variable SNPs across the entire genome of 200 patients with clinical depression and 200 control patients

E) A study that compared the levels of gene expression of a tumor suppressor gene in skin cells versus muscle cells within a single individual

Answer 1

1. False. All the cells in the body have same genome as all the cell originated from the embryo which is a product of fertilization and they were then divided and differentiated according to their respective function.